SCHEMBL21165265

SCHEMBL21165265

CCCO[C@@H](c1cc(Cl)ccc1Cl)[C@H](C)OC(N)=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.37
ALDH1A1 P00352 4/20 0.36
TDP1 Q9NUW8 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
TAS1R3 Q7RTX0 1/20 0.35
TAS1R1 Q7RTX1 1/20 0.35
KDM4E B2RXH2 1/20 0.35
MAPT P10636 2/20 0.34
EPHX1 P07099 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
TSHR P16473 1/20 0.33
SIRT1 Q96EB6 1/20 0.33
MAOB P27338 1/20 0.33
HPGD P15428 1/20 0.33
NLRP1 Q9C000 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15078594 0.85 LMNA (0.34) GAAALDH1A1TAS1R3TAS1R1MAPT
SCHEMBL15078593 0.85 LMNA (0.34) GAAALDH1A1TAS1R3TAS1R1MAPT
SCHEMBL15078354 0.80 TP53 (0.38) GAAALDH1A1TAS1R3TAS1R1KDM4E
SCHEMBL15078355 0.80 TP53 (0.38) GAAALDH1A1TAS1R3TAS1R1KDM4E
SCHEMBL21165420 0.80 MEN1 (0.39) GAAALDH1A1TDP1L3MBTL1KDM4E
SCHEMBL15078398 0.75 LMNA (0.41) EPHX1SMN1; SMN2MEN1KMT2AHPGD
SCHEMBL15078458 0.75 LMNA (0.41) EPHX1SMN1; SMN2MEN1KMT2AHPGD
SCHEMBL15078447 0.75 LMNA (0.41) EPHX1SMN1; SMN2MEN1KMT2AHPGD
SCHEMBL15078585 0.74 LMNA (0.49) L3MBTL1MAPTEPHX1SMN1; SMN2MEN1
SCHEMBL15078552 0.72 LMNA (0.46) ALDH1A1L3MBTL1MAPTEPHX1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10351519-B2 Sulfamate derivative compounds, processes for preparing them and their uses BIO-PHARM SOLUTIONS CO., LTD. (KR) 2019-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10351519-B2 Sulfamate derivative compounds, processes for preparing them and their uses STS, SULT2A1, SULT1A1 GAA 629/4885ALDH1A1 844/4885TDP1 2199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.