SCHEMBL21165358

SCHEMBL21165358

CO[C@H](c1c(Cl)cccc1Cl)[C@@H](C)OS(N)(=O)=O

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
CA9 Q16790 2/20 0.42
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
ACHE P22303 1/20 0.36
APLNR P35414 3/20 0.34
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
NFKB1 P19838 1/20 0.32
PNMT P11086 1/20 0.32
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
GLA P06280 1/20 0.31
BLM P54132 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21165274 1.00 CA1 (0.42) CA1CA2CA9MEN1KMT2A
SCHEMBL21165279 0.85 CA1 (0.34) CA1CA2CA9MEN1KMT2A
SCHEMBL21165270 0.85 CA1 (0.34) CA1CA2CA9MEN1KMT2A
SCHEMBL31744389 0.84 MEN1 (0.38) CA1CA2CA9MEN1KMT2A
SCHEMBL21165470 0.84 MEN1 (0.38) CA1CA2CA9MEN1KMT2A
SCHEMBL20604297 0.83 CA1 (0.41) CA1CA2CA9MEN1KMT2A
SCHEMBL20604299 0.83 CA1 (0.41) CA1CA2CA9MEN1KMT2A
SCHEMBL20604303 0.83 CA1 (0.41) CA1CA2CA9MEN1KMT2A
SCHEMBL20604305 0.83 CA1 (0.41) CA1CA2CA9MEN1KMT2A
SCHEMBL20604267 0.82 APLNR (0.31) CA1CA2ACHEAPLNRCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3423433-B1 SULFAMATE DERIVATIVE COMPOUNDS, PROCESSES FOR PREPARING THEM AND THEIR USES BIO PHARM SOLUTIONS CO LTD (KR) 2025-12-17 EP claimed
EP-3423433-B1 SULFAMATE DERIVATIVE COMPOUNDS, PROCESSES FOR PREPARING THEM AND THEIR USES BIO PHARM SOLUTIONS CO LTD (KR) 2025-12-17 EP disclosed
US-10351519-B2 Sulfamate derivative compounds, processes for preparing them and their uses BIO-PHARM SOLUTIONS CO., LTD. (KR) 2019-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10351519-B2 Sulfamate derivative compounds, processes for preparing them and their uses STS, SULT2A1, SULT1A1 CA1 300/4885CA2 576/4885CA9 674/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.