Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | RARA | P10276 | 1/20 | 0.30 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL85967 | 0.80 | HRH4 (0.54) | HRH4NOS3NOS1NOS2MAPK1 | |
| SCHEMBL14999657 | 0.70 | CYP2A6 (0.46) | HRH4NOS3NOS1NOS2NPC1 | |
| SCHEMBL23298998 | 0.70 | RAB9A (0.45) | HRH4MAPK1NPC1HPGDRAB9A | |
| SCHEMBL2428720 | 0.68 | HRH4 (0.36) | HRH4NOS3NOS1NOS2NPC1 | |
| SCHEMBL8177168 | 0.66 | NOS3 (0.42) | HRH4NOS3NOS1NOS2NPC1 | |
| SCHEMBL30565769 | 0.66 | — | — | |
| SCHEMBL14455164 | 0.66 | MAPK1 (0.44) | HRH4MAPK1NPC1RAB9A | |
| SCHEMBL14455165 | 0.66 | MAPK1 (0.44) | MAPK1NPC1RAB9A | |
| SCHEMBL22075474 | 0.65 | MAPK1 (0.47) | HRH4MAPK1HPGDHTR2AHRH1 | |
| SCHEMBL47849 | 0.65 | NOS3 (0.43) | HRH4NOS3NOS1NOS2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10355227-B2 | Metal complex for phosphorescent OLED | UNIVERSAL DISPLAY CORPORATION (US) | 2019-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10355227-B2 | Metal complex for phosphorescent OLED | OSBPL3, OSBP, OCIAD1 | HRH4 4812/4885NOS3 882/4885NOS1 1938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.