Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | ACHE | P22303 | 2/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21166874 | 1.00 | IKBKB (0.67) | IKBKBKMT2AMEN1ACHEBCHE | |
| SCHEMBL4463210 | 0.80 | KMT2A (1.00) | IKBKBKMT2AMEN1ACHEBCHE | |
| SCHEMBL933876 | 0.80 | IKBKB (1.00) | IKBKBKMT2AMEN1ACHEBCHE | |
| SCHEMBL29929022 | 0.80 | IKBKB (0.52) | IKBKBKMT2AMEN1ACHEBCHE | |
| SCHEMBL13719949 | 0.80 | IKBKB (0.67) | IKBKBKMT2AMEN1ACHEBCHE | |
| SCHEMBL13720053 | 0.80 | IKBKB (1.00) | IKBKBKMT2AMEN1ACHEBCHE | |
| SCHEMBL13719950 | 0.80 | IKBKB (0.67) | IKBKBKMT2AMEN1ACHEBCHE | |
| SCHEMBL932826 | 0.80 | IKBKB (1.00) | IKBKBKMT2AMEN1ACHEBCHE | |
| SCHEMBL30969583 | 0.80 | EGFR (0.69) | ACHEBCHEPTGS2MAPTRAB9A | |
| SCHEMBL14820391 | 0.80 | KMT2A (1.00) | IKBKBKMT2AMEN1ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10357485-B1 | Anti-cancer compound | KING SAUD UNIVERSITY (SA) | 2019-07-23 | — | — | US | claimed |
| US-10357485-B1 | Anti-cancer compound | KING SAUD UNIVERSITY (SA) | 2019-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10357485-B1 | Anti-cancer compound | TP53, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HDAC9 | IKBKB 169/4885KMT2A 1161/4885MEN1 1948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.