Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | ACHE | P22303 | 3/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.55 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 6/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13719949 | 1.00 | IKBKB (0.67) | IKBKBMEN1KMT2AACHEAKR1C3 | |
| SCHEMBL15940019 | 0.88 | MEN1 (0.53) | IKBKBMEN1KMT2AACHEAKR1C3 | |
| SCHEMBL15940018 | 0.88 | MEN1 (0.53) | IKBKBMEN1KMT2AACHEAKR1C3 | |
| SCHEMBL23922931 | 0.83 | MAOB (0.67) | ACHEAKR1C3AKR1C1PTGS2PAX8 | |
| SCHEMBL933876 | 0.80 | IKBKB (1.00) | IKBKBMEN1KMT2AACHEDYRK2 | |
| SCHEMBL21166874 | 0.80 | IKBKB (0.67) | IKBKBMEN1KMT2AACHEDYRK2 | |
| SCHEMBL932826 | 0.80 | IKBKB (1.00) | IKBKBMEN1KMT2AACHEDYRK2 | |
| SCHEMBL21166873 | 0.80 | IKBKB (0.67) | IKBKBMEN1KMT2AACHEDYRK2 | |
| SCHEMBL11841748 | 0.80 | AKR1C3 (0.70) | AKR1C3AKR1C1MAOBEGFRCYP1A2 | |
| SCHEMBL11817550 | 0.80 | AKR1C3 (0.76) | AKR1C3AKR1C1PTGS2MAOBEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9359196-B2 | Antiproliferative compositions comprising curcumin analogs and methods of producing and using same | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2016-06-07 | — | — | US | disclosed |
| US-20120288555-A1 | ANTIPROLIFERATIVE COMPOSITIONS COMPRISING CURCUMIN ANALOGS AND METHODS OF PRODUCING AND USING SAME | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA | 2012-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120288555-A1 | ANTIPROLIFERATIVE COMPOSITIONS COMPRISING CURCUMIN ANALOGS AND METHODS OF PRODUCING AND USING SAME | MCL1, LITAF, CTSA | IKBKB 3061/4885MEN1 1097/4885KMT2A 849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.