SCHEMBL21166975

SCHEMBL21166975

Cn1c2cc(-c3ccccc3)ccc2c(=O)c2cc3c(cc21)c(=O)c1ccc(C(C)(C)C)cc1n3C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.48
L3MBTL1 Q9Y468 4/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
POLB P06746 1/20 0.45
GAA P10253 1/20 0.45
RXFP1 Q9HBX9 1/20 0.45
GRM2 Q14416 1/20 0.44
ATM Q13315 1/20 0.43
RXRA P19793 2/20 0.43
RXRB P28702 2/20 0.43
ALDH1A1 P00352 2/20 0.42
MAPT P10636 2/20 0.42
MAPK1 P28482 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
LIMK1 P53667 1/20 0.42
KIF11 P52732 1/20 0.41
PKM P14618 1/20 0.41
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25523206 0.89 KIF11 (0.51) MAOBL3MBTL1NPC1RAB9APOLB
SCHEMBL21167110 0.89 MAOB (0.57) MAOBL3MBTL1NPC1RAB9APOLB
SCHEMBL25752322 0.87 ATM (0.46) L3MBTL1NPC1RAB9APOLBGAA
SCHEMBL21166970 0.84 L3MBTL1 (0.63) MAOBL3MBTL1NPC1RAB9APOLB
SCHEMBL25058985 0.83 KIF11 (0.53) MAOBL3MBTL1NPC1RAB9AGRM2
SCHEMBL20987318 0.79 MAOB (0.50) MAOBL3MBTL1NPC1RAB9APOLB
SCHEMBL20987444 0.79 ATM (0.56) MAOBL3MBTL1NPC1RAB9APOLB
SCHEMBL25523207 0.78 GRM2 (0.44) GRM2RXRARXRBALDH1A1MAPT
SCHEMBL25752361 0.77 MAT2A (0.45) L3MBTL1NPC1RAB9AATMALDH1A1
SCHEMBL21166969 0.76 MAOB (0.52) MAOBL3MBTL1NPC1RAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190221745-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2019-07-18 US disclosed