Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21167054 | 0.82 | LMNA (0.35) | KDM1A | |
| SCHEMBL30524502 | 0.82 | LMNA (0.35) | KDM1A | |
| SCHEMBL18398486 | 0.80 | CA1 (0.32) | KDM1A | |
| SCHEMBL30881834 | 0.77 | KCNN4 (0.31) | — | |
| SCHEMBL16268577 | 0.76 | DRD1 (0.34) | — | |
| SCHEMBL31535909 | 0.76 | TRPV4 (0.37) | — | |
| SCHEMBL6684943 | 0.76 | MAPT (0.36) | KMT2A | |
| SCHEMBL9562029 | 0.76 | KMT2A (0.33) | KMT2A | |
| SCHEMBL246292 | 0.75 | SLC6A4 (0.47) | KDM1A | |
| SCHEMBL983555 | 0.75 | GRIN2B (0.41) | RXRAGRIN1GRIN2BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111315744-B | Heteroaryl tetrahydropyridine compound, preparation method, pharmaceutical composition and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-111315744-A | Heteroaryl tetrahydropyridine compound, preparation method thereof, pharmaceutical composition and application thereof | 四川科伦博泰生物医药股份有限公司 | 2020-06-19 | — | — | CN | disclosed |
| WO-2019137201-A1 | HETEROARYLO TETRAHYDROPYRIDINE COMPOUND AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND APPLICATION THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-07-18 | — | — | WO | disclosed |