Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 6/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 3/20 | 0.38 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22475857 | 0.89 | MET (0.38) | METKEAP1NAMPTPAK1NQO2 | |
| SCHEMBL21167673 | 0.89 | CSF1R (0.45) | METKEAP1NAMPTPAK1NQO2 | |
| SCHEMBL22475697 | 0.87 | MET (0.51) | METKEAP1PAK1NQO2MKNK1 | |
| SCHEMBL22475807 | 0.86 | MET (0.42) | METKEAP1NAMPTPAK1NQO2 | |
| SCHEMBL22475716 | 0.86 | MET (0.41) | METKEAP1PAK1MKNK1TRIM33 | |
| SCHEMBL24591043 | 0.82 | MET (0.54) | METKEAP1NAMPTPAK1MKNK1 | |
| SCHEMBL21167805 | 0.81 | MET (0.54) | METKEAP1NAMPTPAK1MKNK1 | |
| SCHEMBL21167408 | 0.79 | MKNK1 (0.53) | METKEAP1NAMPTPAK1MKNK1 | |
| SCHEMBL21167714 | 0.79 | MET (0.44) | MET | |
| SCHEMBL21167583 | 0.76 | MET (0.49) | METKEAP1NAMPTPAK1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3511330-A1 | SYNTHETIC INTERMEDIATE USEFUL IN THE PREPARATION OF TRIAZOLOPYRIDINE C-MET INHIBITORS | Hutchison Medipharma Limited (CN) | 2019-07-17 | — | — | EP | disclosed |