Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 4/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 4/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.34 |
| ▸ | KDR | P35968 | 4/20 | 0.34 |
| ▸ | IKBKE | Q14164 | 5/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 5/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.32 |
| ▸ | LIPC | P11150 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21167440 | 0.90 | CSF1R (0.42) | SYKFEN1FGFR1FGFR2FGFR4 | |
| SCHEMBL22475903 | 0.87 | SYK (0.37) | SYKFEN1FGFR1FGFR2FGFR4 | |
| SCHEMBL21167411 | 0.79 | CSF1R (0.41) | SYKFEN1FGFR1FGFR2FGFR4 | |
| SCHEMBL22475803 | 0.77 | SYK (0.35) | SYKFEN1FGFR1FGFR2FGFR4 | |
| SCHEMBL21167672 | 0.77 | CSF1R (0.56) | FGFR1FGFR2FGFR3KDRCSF1R | |
| SCHEMBL21167475 | 0.75 | MET (0.45) | SYKFEN1FGFR1FGFR2FGFR4 | |
| SCHEMBL22475817 | 0.75 | CSF1R (0.45) | SYKFGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL23127952 | 0.75 | MET (0.48) | — | |
| SCHEMBL24591027 | 0.75 | CSF1R (0.39) | FGFR1FGFR2FGFR3CSF1RALOX5AP | |
| SCHEMBL22475775 | 0.73 | MET (0.34) | CSF1RALOX5APTYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3795573-B1 | CERTAIN TRIAZOLOPYRAZINES, COMPOSITIONS THEREOF AND METHODS OF USE THEREFOR | HUTCHISON MEDIPHARMA LTD (CN) | 2022-07-06 | — | — | EP | disclosed |
| EP-3511330-A1 | SYNTHETIC INTERMEDIATE USEFUL IN THE PREPARATION OF TRIAZOLOPYRIDINE C-MET INHIBITORS | Hutchison Medipharma Limited (CN) | 2019-07-17 | — | — | EP | disclosed |