Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 13/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 12/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.43 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | ADAM8 | P78325 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25100584 | 0.92 | SIRT2 (0.43) | SIRT2SIRT1SIRT3SIRT5SPHK1 | |
| SCHEMBL19443237 | 0.92 | SIRT2 (0.43) | SIRT2SIRT1SIRT3SIRT5SPHK1 | |
| SCHEMBL20327986 | 0.92 | SIRT2 (0.43) | SIRT2SIRT1SIRT3SIRT5SPHK1 | |
| SCHEMBL20861964 | 0.91 | SIRT2 (0.47) | SIRT2SIRT1SIRT3SIRT5SPHK1 | |
| SCHEMBL25100437 | 0.89 | ROCK2 (0.42) | SIRT2SIRT1SIRT3SIRT5SPHK1 | |
| SCHEMBL25765345 | 0.89 | SIRT2 (0.42) | SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL24728294 | 0.88 | SIRT2 (0.46) | SIRT2SIRT1SIRT3SIRT5ADAM10 | |
| SCHEMBL19633304 | 0.86 | SPHK1 (0.41) | SIRT2SIRT1SIRT3SIRT5SPHK1 | |
| SCHEMBL24094770 | 0.86 | SIRT2 (0.44) | SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL20043710 | 0.86 | SIRT2 (0.46) | SIRT2SIRT1SIRT3SIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928902-B1 | CONJUGATE COMPOUNDS | VICTORIA LINK LTD (NZ) | 2019-07-17 | — | — | EP | disclosed |