Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | ADAM8 | P78325 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 8/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23221828 | 0.90 | ADAM10 (0.39) | ADAM10MMP2MMP9MMP12MMP14 | |
| SCHEMBL18431308 | 0.89 | FURIN (0.41) | ADAM10MMP2MMP9MMP12MMP14 | |
| SCHEMBL22810892 | 0.89 | SIRT2 (0.41) | ADAM10MMP2MMP9MMP12MMP14 | |
| SCHEMBL21883411 | 0.87 | SIRT2 (0.39) | SIRT2SIRT1SIRT3SIRT5NPC1 | |
| SCHEMBL24329149 | 0.87 | SIRT2 (0.41) | ADAM10MMP2MMP9MMP12MMP14 | |
| SCHEMBL19389191 | 0.86 | SIRT2 (0.41) | SIRT2SIRT1SIRT3SIRT5SMN1; SMN2 | |
| SCHEMBL20844980 | 0.86 | LTA4H (0.47) | SPHK1ADAM10MMP2MMP9MMP12 | |
| SCHEMBL21167799 | 0.86 | SIRT2 (0.44) | SPHK1ADAM10MMP2MMP9MMP12 | |
| SCHEMBL25100584 | 0.85 | SIRT2 (0.43) | SPHK1ADAM10MMP2MMP9MMP12 | |
| SCHEMBL19443237 | 0.85 | SIRT2 (0.43) | SPHK1ADAM10MMP2MMP9MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023173026-A1 | ANTIBODY-DRUG CONJUGATES AND USES THEREOF | SORRENTO THERAPEUTICS, INC. (US) | 2023-09-14 | — | — | WO | disclosed |
| EP-3753578-A1 | CYTOTOXIC PEPTIDES AND CONJUGATES THEREOF | Novartis AG (CH) | 2020-12-23 | — | — | EP | disclosed |
| WO-2017201204-A1 | ANTI-cMet ANTIBODY DRUG CONJUGATES AND METHODS FOR THEIR USE | ABBVIE BIOTHERAPEUTICS INC. (US) | 2017-11-23 | — | — | WO | disclosed |