Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 3/20 | 0.41 |
| ▸ | ACE | P12821 | 8/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21168334 | 0.93 | MME (0.40) | FKBP1AACEF2 | |
| SCHEMBL21168335 | 0.93 | MME (0.40) | FKBP1AACEF2 | |
| SCHEMBL21168290 | 0.91 | FABP4 (0.32) | FKBP1A | |
| SCHEMBL21168289 | 0.91 | FABP4 (0.32) | FKBP1A | |
| SCHEMBL23351265 | 0.90 | FABP4 (0.32) | FKBP1AACE | |
| SCHEMBL21168340 | 0.89 | ACE (0.33) | FKBP1AACE | |
| SCHEMBL21168362 | 0.89 | ACE (0.33) | FKBP1AACE | |
| SCHEMBL21168353 | 0.89 | VSIR (0.35) | FKBP1AACE | |
| SCHEMBL21168342 | 0.89 | VSIR (0.35) | FKBP1AACE | |
| SCHEMBL21168352 | 0.89 | VSIR (0.35) | FKBP1AACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190218252-A1 | 1,2,4-Oxadiazole Compounds as Inhibitors of CD47 Signalling | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2019-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190218252-A1 | 1,2,4-Oxadiazole Compounds as Inhibitors of CD47 Signalling | CD47, HIF1AN, PIK3R5 | FKBP1A 971/4885ACE 4810/4885LMNA 3138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.