SCHEMBL211698

SCHEMBL211698

Cn1cnc2cc([N+](=O)[O-])ccc21

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.61
ALDH1A1 P00352 8/20 0.60
MAPT P10636 7/20 0.57
PKM P14618 2/20 0.57
HPGD P15428 1/20 0.57
KMT2A Q03164 2/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
KDM4E B2RXH2 1/20 0.52
GAA P10253 1/20 0.52
HTT P42858 2/20 0.51
FGFR1 P11362 1/20 0.49
GFER P55789 1/20 0.46
BRD4 O60885 1/20 0.45
KCNH2 Q12809 1/20 0.45
GRM5 P41594 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1489409 0.87 L3MBTL1 (0.66) L3MBTL1ALDH1A1MAPTPKMHPGD
SCHEMBL24569513 0.84 L3MBTL1 (0.49) L3MBTL1ALDH1A1MAPTPKMHPGD
SCHEMBL29888172 0.81 L3MBTL1 (0.46) L3MBTL1ALDH1A1MAPTPKMHPGD
SCHEMBL24570249 0.81 L3MBTL1 (0.46) L3MBTL1ALDH1A1MAPTPKMHPGD
SCHEMBL29887959 0.81 PDE7A (0.55) L3MBTL1ALDH1A1MAPTPKMHPGD
SCHEMBL24569515 0.81 PDE7A (0.55) L3MBTL1ALDH1A1MAPTPKMHPGD
SCHEMBL19911367 0.81 ALDH1A1 (0.57) L3MBTL1ALDH1A1MAPTPKMHPGD
SCHEMBL19911366 0.80 PKM (0.68) L3MBTL1ALDH1A1MAPTPKMHPGD
SCHEMBL19911364 0.80 MAPT (0.61) L3MBTL1ALDH1A1MAPTPKMHPGD
SCHEMBL594361 0.80 ALDH1A1 (0.60) L3MBTL1ALDH1A1MAPTPKMHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3404056-B1 METHOD FOR PRODUCING THERMOPLASTIC ELASTOMER COMPOSITION ZEON CORP (JP) 2025-06-11 EP disclosed
EP-3101065-B1 CROSS-LINKABLE NITRILE RUBBER COMPOSITION AND CROSS-LINKED RUBBER ZEON CORP (JP) 2025-05-28 EP disclosed
US-12202923-B2 Nitrile-group-containing copolymer rubber ZEON CORPORATION (JP) 2025-01-21 US disclosed
US-12037636-B2 Polynucleotide synthesis method, kit and system OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2024-07-16 US disclosed
CN-114555660-B Nitrile group-containing copolymer rubber 日本瑞翁株式会社 2024-06-11 CN disclosed
EP-3305817-B2 NITRILE GROUP CONTAINING, HIGHLY SATURATED COPOLYMER RUBBER ZEON CORP (JP) 2023-12-27 EP disclosed
EP-3744739-B1 METHOD FOR PRODUCING CARBOXY GROUP-CONTAINING HYDROGENATED NITRILE RUBBER ZEON CORP (JP) 2023-12-27 EP disclosed
US-11639408-B2 Nitrile group-containing copolymer rubber ZEON CORPORATION (JP) 2023-05-02 US disclosed
EP-3604433-B1 CROSSLINKABLE RUBBER COMPOSITION AND CROSSLINKED RUBBER OBJECT ZEON CORP (JP) 2023-04-19 EP disclosed
EP-3176190-B1 NITRILE-GROUP-CONTAINING COPOLYMER RUBBER, CROSSLINKABLE RUBBER COMPOSITION, AND CROSSLINKED RUBBER ZEON CORP (JP) 2023-03-29 EP disclosed
US-7253204-B2 Antiproliferative agents METHYLGENE INC. (CA) 2007-08-07 US disclosed
US-7253204-B2 Antiproliferative agents METHYLGENE INC. (CA) 2007-08-07 US disclosed
WO-2007016354-A1 MULTICYCLIC SULFONAMIDE COMPOUNDS AS INHIBITORS OF HISTONE DEACETYLASE FOR THE TREATMENT OF DISEASE KALYPSYS, INC. (US) 2007-02-08 WO disclosed
US-20070027184-A1 Multicyclic sulfonamide compounds as inhibitors of histone deacetylase for the treatment of disease KALYPSYS, INC. 2007-02-01 US disclosed
EP-1735319-A1 INHIBITORS OF HISTONE DEACETYLASE Methylgene, Inc. (CA) 2006-12-27 EP disclosed
WO-2006123145-A1 ANTIFUNGAL AGENTS F2G LTD (GB) 2006-11-23 WO disclosed
US-20050245518-A1 Antiproliferative agents METHYLGENE, INC. 2005-11-03 US disclosed
WO-2005092899-A1 INHIBITORS OF HISTONE DEACETYLASE METHYLGENE INC. (CA) 2005-10-06 WO disclosed
WO-2005092899-A1 INHIBITORS OF HISTONE DEACETYLASE METHYLGENE INC. (CA) 2005-10-06 WO disclosed
WO-2005035526-A1 BICYCLIC COMPOUNDS AND THEIR THERAPEUTIC USE ARGENTA DISCOVERY LTD. (GB) 2005-04-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070027184-A1 Multicyclic sulfonamide compounds as inhibitors of histone deacetylase for the treatment of disease HDAC6, HDAC5, HDAC7 L3MBTL1 3403/4885ALDH1A1 1241/4885MAPT 1682/4885
US-20050245518-A1 Antiproliferative agents HDAC1, HDAC11, HDAC5 L3MBTL1 1607/4885ALDH1A1 758/4885MAPT 3905/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.