Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.68 |
| ▸ | TGM2 | P21980 | 1/20 | 0.68 |
| ▸ | KRAS | P01116 | 8/20 | 0.66 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.63 |
| ▸ | IMPDH2 | P12268 | 4/20 | 0.60 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.60 |
| ▸ | HINT1 | P49773 | 1/20 | 0.59 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.58 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.58 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.58 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.57 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18759022 | 0.96 | NT5E (0.73) | NT5ETGM2KRASFUT5IMPDH2 | |
| SCHEMBL21184321 | 0.94 | NT5E (0.68) | NT5ETGM2KRASFUT5IMPDH2 | |
| SCHEMBL29160869 | 0.93 | NT5E (0.77) | NT5ETGM2KRASFUT5IMPDH2 | |
| SCHEMBL14659957 | 0.93 | NT5E (0.77) | NT5ETGM2KRASFUT5IMPDH2 | |
| SCHEMBL18258303 | 0.93 | NT5E (0.77) | NT5ETGM2KRASFUT5IMPDH2 | |
| SCHEMBL21413953 | 0.92 | NT5E (0.70) | NT5ETGM2KRASFUT5IMPDH2 | |
| SCHEMBL24322582 | 0.89 | TGM2 (0.66) | NT5ETGM2KRASFUT5IMPDH2 | |
| SCHEMBL18769517 | 0.89 | P2RY2 (0.73) | NT5ETGM2KRASFUT5IMPDH2 | |
| SCHEMBL8202050 | 0.89 | NT5E (0.83) | NT5ETGM2KRASFUT5IMPDH2 | |
| SCHEMBL2166452 | 0.89 | TGM2 (0.79) | NT5ETGM2KRASFUT5IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10570388-B2 | Phosphate replacement MRNA cap analogs | MODERNATX, INC. (US) | 2020-02-25 | — | — | US | disclosed |
| US-10563195-B2 | Phosphate replacement mRNA cap analogs | MODERNATX, INC. (US) | 2020-02-18 | — | — | US | disclosed |
| US-20190218546-A1 | MRNA CAP ANALOGS WITH MODIFIED PHOSPHATE LINKAGE | MODERNATX, INC. | 2019-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10570388-B2 | Phosphate replacement MRNA cap analogs | RNGTT, RNMT, CPSF6 | NT5E 518/4885TGM2 3627/4885KRAS 2714/4885 |
| US-20190218546-A1 | MRNA CAP ANALOGS WITH MODIFIED PHOSPHATE LINKAGE | RNGTT, RNMT, CPSF7 | NT5E 504/4885TGM2 3711/4885KRAS 3503/4885 |
| US-10563195-B2 | Phosphate replacement mRNA cap analogs | RNGTT, RNMT, CPSF6 | NT5E 518/4885TGM2 3627/4885KRAS 2714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.