Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 5/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.68 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.68 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.68 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.65 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.65 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.63 |
| ▸ | DPP4 | P27487 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.63 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.63 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29385449 | 1.00 | AHCY (0.68) | AHCYHIF1ATMEM97SIGMAR1ADORA2A | |
| SCHEMBL1757011 | 1.00 | AHCY (0.68) | AHCYHIF1ATMEM97SIGMAR1ADORA2A | |
| SCHEMBL6902907 | 0.99 | AHCY (0.67) | AHCYHIF1ATMEM97SIGMAR1ADORA2A | |
| SCHEMBL6902911 | 0.99 | AHCY (0.67) | AHCYHIF1ATMEM97SIGMAR1ADORA2A | |
| SCHEMBL6902895 | 0.99 | AHCY (0.67) | AHCYHIF1ATMEM97SIGMAR1ADORA2A | |
| SCHEMBL30139992 | 0.91 | AHCY (0.68) | AHCYHIF1ATMEM97SIGMAR1ADORA2A | |
| SCHEMBL4520806 | 0.91 | AHCY (0.68) | AHCYHIF1ATMEM97SIGMAR1ADORA2A | |
| SCHEMBL4520798 | 0.91 | AHCY (0.68) | AHCYHIF1ATMEM97SIGMAR1ADORA2A | |
| SCHEMBL30139993 | 0.91 | AHCY (0.68) | AHCYHIF1ATMEM97SIGMAR1ADORA2A | |
| SCHEMBL5620791 | 0.90 | AHCY (0.58) | AHCYHIF1ATMEM97SIGMAR1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4224438-A | CARDIOTONIC AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1980-09-23 | — | — | US | claimed |
| JP-58167598-A | — | — | None | — | — | JP | disclosed |
| JP-58172318-A | — | — | None | — | — | JP | disclosed |
| US-9176064-B2 | Bisubstrate fluorescent probes for protein kinase CK2 | UNIVERSITY OF TARTU (EE) | 2015-11-03 | — | — | US | disclosed |
| US-20140057291-A1 | BISUBSTRATE FLUORESCENT PROBES FOR PROTEIN KINASE CK2 | UNIVERSITY OF TARTU (EE) | 2014-02-27 | — | — | US | disclosed |
| EP-2700946-A1 | Bisubstrate fluorescent probes for protein kinase CK2 | University of Tartu (EE) | 2014-02-26 | — | — | EP | disclosed |
| EP-2471803-B1 | Compounds that interact with kinases | ALCHEMIA LTD (AU) | 2013-11-27 | — | — | EP | disclosed |
| EP-1179050-B1 | METHOD FOR THE PURIFICATION OF PROTEIN KINASE BY AFFINITY CHROMATOGRAPHY | UNIV TARTU (EE) | 2012-12-19 | — | — | EP | disclosed |
| US-8158376-B2 | Bisubstrate fluorescent probe binding to protein kinases | UNIVERSITY OF TARTU (EE) | 2012-04-17 | — | — | US | disclosed |
| US-20100233743-A1 | BISUBSTRATE FLUORESCENT PROBE BINDING TO PROTEIN KINASES | UNIVERSITY OF TARTU (EE) | 2010-09-16 | — | — | US | disclosed |
| JP-S58167598-A | ADENOSINE DERIVATIVE AND ITS PREPARATION | TANABE SEIYAKU CO LTD | 1983-10-03 | — | — | JP | disclosed |
| US-4385112-A | CULTURES, PSEUDOMONAS, QUANTITATIVE NUCLEOSIDE ASSAY, MAKING NUCLEOSIDE-5-CARBOXYLIC ACIDS | TOYO JOZO KABUSHIKI KAISHA (JP) | 1983-05-24 | — | — | US | disclosed |
| US-4224438-A | CARDIOTONIC AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1980-09-23 | — | — | US | disclosed |
| US-4224438-A | CARDIOTONIC AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1980-09-23 | — | — | US | disclosed |
| US-4167565-A | Adenosine-5'-carboxamides and method of use | ABBOTT LABORATORIES (US) | 1979-09-11 | — | — | US | disclosed |
| US-4029884-A | Adenosine-5'-carboxylic acid amides | ABBOTT LABORATORIES (US) | 1977-06-14 | — | — | US | disclosed |
| US-3971849-A | 1,N6 -etheno-5'-adenosine carboxylates for increasing coronary sinus partial pressure of oxygen | ABBOTT LABORATORIES (US) | 1976-07-27 | — | — | US | disclosed |
| US-3966917-A | ADENOSINE-5'-CARBOXAMIDES | ABBOTT LABORATORIES (US) | 1976-06-29 | — | — | US | disclosed |
| US-3855204-A | PROCESS FOR PREPARING ADENOSINE-5{40 -CARBOXYLIC ACID, ETHYL ESTER | ABBOTT LAB | 1974-12-17 | — | — | US | disclosed |
| US-3855205-A | PROCESS FOR PREPARING ADENOSINE-5{40 -CARBOXYLATES | ABBOTT LAB | 1974-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100233743-A1 | BISUBSTRATE FLUORESCENT PROBE BINDING TO PROTEIN KINASES | ADK, PRKCH, DMPK | AHCY 1747/4885HIF1A 2475/4885TMEM97 2390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.