Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 8/20 | 0.68 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.68 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.68 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.63 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.63 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.61 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.61 |
| ▸ | DPP4 | P27487 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30139993 | 1.00 | AHCY (0.68) | AHCYADORA2BHSP90B1ADORA2AHIF1A | |
| SCHEMBL4520806 | 1.00 | AHCY (0.68) | AHCYADORA2BHSP90B1ADORA2AHIF1A | |
| SCHEMBL30139992 | 1.00 | AHCY (0.68) | AHCYADORA2BHSP90B1ADORA2AHIF1A | |
| SCHEMBL2117335 | 0.91 | AHCY (0.68) | AHCYADORA2BHSP90B1ADORA2AHIF1A | |
| SCHEMBL1757011 | 0.91 | AHCY (0.68) | AHCYADORA2BHSP90B1ADORA2AHIF1A | |
| SCHEMBL29385449 | 0.91 | AHCY (0.68) | AHCYADORA2BHSP90B1ADORA2AHIF1A | |
| SCHEMBL6902907 | 0.90 | AHCY (0.67) | AHCYADORA2BHSP90B1ADORA2AHIF1A | |
| SCHEMBL6902895 | 0.90 | AHCY (0.67) | AHCYADORA2BHSP90B1ADORA2AHIF1A | |
| SCHEMBL6902911 | 0.90 | AHCY (0.67) | AHCYADORA2BHSP90B1ADORA2AHIF1A | |
| SCHEMBL6902902 | 0.89 | NT5E (0.63) | AHCYADORA2BHSP90B1ADORA2AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4224438-A | CARDIOTONIC AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1980-09-23 | — | — | US | claimed |
| JP-63201196-A | — | — | None | — | — | JP | disclosed |
| US-12378248-B2 | A1 adenosine receptor agonists and methods of use thereof | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2025-08-05 | — | — | US | disclosed |
| US-20230102924-A1 | Methods of Treating Cancer Using Checkpoint Inhibitors in Combination with Purine Cleaving Enzymes | UNIV EMORY (US) | 2023-03-30 | — | — | US | disclosed |
| US-20220024926-A1 | A1 ADENOSINE RECEPTOR AGONISTS AND METHODS OF USE THEREOF | THE UNITED STATES OF AMERICA,AS REPRESENTED BY THE SECRETARY,DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2022-01-27 | — | — | US | disclosed |
| WO-2020118139-A1 | A1 ADENOSINE RECEPTOR AGONISTS AND METHODS OF USE THEREOF | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2020-06-11 | — | — | WO | disclosed |
| WO-2009092516-A2 | METHODS, COMPOSITIONS, UNIT DOSAGE FORMS, AND KITS FOR PHARMACOLOGIC STRESS TESTING WITH REDUCED SIDE EFFECTS | ADENOBIO N.V. (NL) | 2009-07-30 | — | — | WO | disclosed |
| US-20090185973-A1 | METHODS, COMPOSITIONS, UNIT DOSAGE FORMS, AND KITS FOR PHARMACOLOGIC STRESS TESTING WITH REDUCED SIDE EFFECTS | ADENOBIO N.V. (NL) | 2009-07-23 | — | — | US | disclosed |
| US-7488598-B2 | Mutant purine nucleoside phosphorylase proteins and cellular delivery thereof | CORNELL CENTER FOR TECHNOLOGY ENTERPRISE AND COMMERCIALIZATION (US) | 2009-02-10 | — | — | US | disclosed |
| US-7037718-B2 | Mutant purine nucleoside phosphorylase proteins and cellular delivery thereof | CORNELL RESEARCH FOUNDATION, INC. (US) | 2006-05-02 | — | — | US | disclosed |
| EP-0179630-A2 | N6-acenaphthyl adenosines and analogs thereof | WARNER-LAMBERT COMPANY (US) | 1986-04-30 | — | — | EP | disclosed |
| EP-0179667-A2 | N6-substituted adenosines | WARNER-LAMBERT COMPANY (US) | 1986-04-30 | — | — | EP | disclosed |
| WO-1986000310-A1 | N-6 AND 5'-N SUBSTITUTED CARBOXAMIDOADENOSINE DERIVATIVES AS CARDIAC VASODILATORS AND ANTIHYPERTENSIVE AGENTS, AND PROCESS FOR MAKING SAID COMPOUNDS | NELSON RESEARCH AND DEVELOPMENT COMPANY (US) | 1986-01-16 | — | — | WO | disclosed |
| EP-0139358-A2 | N6-substituted diarylalkyl adenosines, processes for their production and pharmaceutical compositions comprising the same | WARNER-LAMBERT COMPANY (US) | 1985-05-02 | — | — | EP | disclosed |
| US-4224438-A | CARDIOTONIC AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1980-09-23 | — | — | US | disclosed |
| US-4167565-A | Adenosine-5'-carboxamides and method of use | ABBOTT LABORATORIES (US) | 1979-09-11 | — | — | US | disclosed |
| US-4104462-A | Cardioactive adenosine nitrates | HOFFMANN-LA ROCHE INC. (US) | 1978-08-01 | — | — | US | disclosed |
| US-4029884-A | Adenosine-5'-carboxylic acid amides | ABBOTT LABORATORIES (US) | 1977-06-14 | — | — | US | disclosed |
| US-3966917-A | ADENOSINE-5'-CARBOXAMIDES | ABBOTT LABORATORIES (US) | 1976-06-29 | — | — | US | disclosed |
| US-3966917-A | ADENOSINE-5'-CARBOXAMIDES | ABBOTT LABORATORIES (US) | 1976-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12378248-B2 | A1 adenosine receptor agonists and methods of use thereof | ADORA1, ADORA2A, ADORA2B | AHCY 525/4885ADORA2B 3/4885HSP90B1 1538/4885 |
| US-20220024926-A1 | A1 ADENOSINE RECEPTOR AGONISTS AND METHODS OF USE THEREOF | ADORA1, ADORA2A, ADORA2B | AHCY 525/4885ADORA2B 3/4885HSP90B1 1538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.