SCHEMBL21176405

SCHEMBL21176405

c1ccc(-n2c3ccccc3c3cc(-c4ccc5c(c4)c4ccccc4n5-c4ccc5oc6nc7c8ccccc8c8ccccc8c7nc6c5c4)ccc32)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.39
KDM4E B2RXH2 2/20 0.39
ATM Q13315 1/20 0.39
SMN1; SMN2 Q16637 5/20 0.34
LMNA P02545 2/20 0.34
PTGER4 P35408 1/20 0.34
SIRT2 Q8IXJ6 1/20 0.32
SIRT1 Q96EB6 1/20 0.32
ALDH1A1 P00352 3/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
CA9 Q16790 2/20 0.31
EDNRB P24530 1/20 0.31
EDNRA P25101 1/20 0.31
TBK1 Q9UHD2 1/20 0.31
HPGD P15428 3/20 0.31
MEN1 O00255 2/20 0.31
MAPK1 P28482 2/20 0.31
KMT2A Q03164 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30929924 1.00 L3MBTL1 (0.39) L3MBTL1KDM4EATMSMN1; SMN2LMNA
SCHEMBL21185886 0.97 KDM4E (0.37) L3MBTL1KDM4EATMSMN1; SMN2LMNA
SCHEMBL21186095 0.95 KDM4E (0.38) L3MBTL1KDM4EATMSMN1; SMN2LMNA
SCHEMBL29839420 0.95 KDM4E (0.38) L3MBTL1KDM4EATMSMN1; SMN2LMNA
SCHEMBL21186082 0.94 KDM4E (0.39) L3MBTL1KDM4EATMSMN1; SMN2LMNA
SCHEMBL21185878 0.94 KDM4E (0.39) L3MBTL1KDM4EATMSMN1; SMN2LMNA
SCHEMBL21185885 0.92 KDM4E (0.36) L3MBTL1KDM4EATMSMN1; SMN2LMNA
SCHEMBL21185985 0.92 KDM4E (0.38) L3MBTL1KDM4EATMSMN1; SMN2LMNA
SCHEMBL21185980 0.91 KDM4E (0.37) L3MBTL1KDM4EATMSMN1; SMN2LMNA
SCHEMBL21176412 0.90 KDM4E (0.36) L3MBTL1KDM4EATMSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12096690-B2 Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-09-17 US disclosed
US-20230027613-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2023-01-26 US disclosed
US-20230027613-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2023-01-26 US disclosed
US-11462696-B2 Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2022-10-04 US disclosed
US-20190229278-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-07-25 US disclosed
US-20190229278-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-07-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11462696-B2 Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device NFE2L2, AOX1, CCNE2 L3MBTL1 295/4885KDM4E 2777/4885ATM 2315/4885
US-20230027613-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device NFE2L2, AOX1, CCNE2 L3MBTL1 295/4885KDM4E 2777/4885ATM 2315/4885
US-20190229278-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device NFE2L2, AOX1, CCNE2 L3MBTL1 295/4885KDM4E 2777/4885ATM 2315/4885
US-12096690-B2 Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device NFE2L2, AOX1, CCNE2 L3MBTL1 295/4885KDM4E 2777/4885ATM 2315/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.