SCHEMBL21176909 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	RAB9A	P51151	5/20	0.46

▸	NPC1	O15118	4/20	0.46

▸	SMN1; SMN2	Q16637	4/20	0.46

▸	GAA	P10253	2/20	0.46

▸	POLB	P06746	2/20	0.43

▸	TP53	P04637	2/20	0.41

▸	ALDH1A1	P00352	1/20	0.40

▸	LMNA	P02545	1/20	0.39

▸	L3MBTL1	Q9Y468	1/20	0.39

▸	MAPT	P10636	1/20	0.38

▸	CCR2	P41597	3/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL21176908	1.00	RAB9A (0.46)	RAB9ANPC1SMN1; SMN2GAAPOLB
SCHEMBL21187143	0.86	RAB9A (0.46)	RAB9ANPC1SMN1; SMN2GAAPOLB
SCHEMBL21187183	0.86	RAB9A (0.46)	RAB9ANPC1SMN1; SMN2GAAPOLB
SCHEMBL21187129	0.81	RAB9A (0.49)	RAB9ANPC1SMN1; SMN2GAAPOLB
SCHEMBL21177091	0.78	NPC1 (0.45)	RAB9ANPC1SMN1; SMN2GAAALDH1A1
SCHEMBL21177092	0.78	NPC1 (0.45)	RAB9ANPC1SMN1; SMN2GAAALDH1A1
SCHEMBL21176799	0.77	KMT2A (0.43)	RAB9ANPC1SMN1; SMN2POLBALDH1A1
SCHEMBL21176800	0.77	KMT2A (0.43)	RAB9ANPC1SMN1; SMN2POLBALDH1A1
SCHEMBL21176804	0.71	NPC1 (0.47)	RAB9ANPC1SMN1; SMN2POLBALDH1A1
SCHEMBL21187148	0.71	MAOA (0.45)	RAB9ANPC1SMN1; SMN2GAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2019141095-A1	AMIDINE AND GUANIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF	四川科伦博泰生物医药股份有限公司	2019-07-25	—	—	WO	disclosed