Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 3/20 | 0.44 |
| ▸ | FPR1 | P21462 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21187213 | 0.88 | NPC1 (0.48) | KMT2AEPHX2MAPTNPC1RAB9A | |
| SCHEMBL21187135 | 0.87 | EPHX2 (0.40) | KMT2AEPHX2MAPTNPC1RAB9A | |
| SCHEMBL21187151 | 0.86 | EPHX2 (0.42) | KMT2AFPR2FPR1EPHX2MAPT | |
| SCHEMBL21187183 | 0.85 | RAB9A (0.46) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL21187143 | 0.85 | RAB9A (0.46) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL21187132 | 0.82 | MAOA (0.48) | MAOAMAOBKMT2AFPR2FPR1 | |
| SCHEMBL21187136 | 0.78 | SMN1; SMN2 (0.40) | KMT2AFPR2FPR1EPHX2MAPT | |
| SCHEMBL21187130 | 0.77 | SMN1; SMN2 (0.39) | KMT2AFPR2FPR1EPHX2MAPT | |
| SCHEMBL21177092 | 0.73 | NPC1 (0.45) | KMT2AEPHX2MAPTNPC1RAB9A | |
| SCHEMBL20838628 | 0.72 | EPHX2 (0.65) | MAOAMAOBKMT2AFPR2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141095-A1 | AMIDINE AND GUANIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-07-25 | — | — | WO | disclosed |