Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | PDE4A | P27815 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 6/20 | 0.38 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.37 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9277352 | 0.85 | IDO1 (0.50) | IDO1USP30UHRF1TLR7TLR8 | |
| SCHEMBL12093743 | 0.82 | IDO1 (0.45) | IDO1USP30UHRF1TLR7TLR8 | |
| SCHEMBL12093732 | 0.82 | IDO1 (0.45) | IDO1USP30UHRF1TLR7TLR8 | |
| SCHEMBL18705765 | 0.81 | PDE4A (0.45) | ESR2PDE4APDE4BPDE4CPDE4D | |
| Bicarbonate SCHEMBL9280862 | 0.81 | IDO1 (0.54) | IDO1USP30UHRF1TLR7TLR8 | |
| Cyanide SCHEMBL27912025 | 0.80 | IDO1 (0.47) | IDO1USP30UHRF1TLR7TLR8 | |
| SCHEMBL22402327 | 0.80 | IDO1 (0.44) | IDO1USP30UHRF1TLR7TLR8 | |
| SCHEMBL22048047 | 0.80 | PDE4A (0.49) | ESR2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5584522 | 0.79 | IDO1 (0.43) | IDO1USP30UHRF1TLR7TLR8 | |
| SCHEMBL21381385 | 0.78 | ESR2 (0.46) | ESR2PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110092750-B | Pentafluoro sulfanyl substituted amide compound, preparation method and application thereof in medicine | 北京诺诚健华医药科技有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-111247119-B | Amidine and guanidine derivatives, preparation method and application thereof in medicines | 四川科伦博泰生物医药股份有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-112334458-B | 3-indazolinone compound, preparation method and application thereof in medicine and pharmacology | 北京诺诚健华医药科技有限公司 | 2022-11-08 | — | — | CN | disclosed |
| US-11389445-B2 | Pentafluorosulfanyl-substituted amide derivatives, preparation methods thereof and medical uses thereof | BEIJING INNOCARE PHARMA TECH CO., LTD. (CN) | 2022-07-19 | — | — | US | disclosed |
| CN-107674013-B | Polycyclic compound, preparation method, pharmaceutical composition and application thereof | 上海迪诺医药科技有限公司 | 2022-05-24 | — | — | CN | disclosed |
| CN-111630043-B | Compound containing ring, preparation method and application thereof in medicine | 四川科伦博泰生物医药股份有限公司 | 2022-02-15 | — | — | CN | disclosed |
| US-20210221808-A1 | 3-OXAZOLINONE COMPOUND, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL APPLICATION THEREOF | BEIJING INNOCARE PHARMA TECH CO., LTD. (CN) | 2021-07-22 | — | — | US | disclosed |
| US-20210221808-A1 | 3-OXAZOLINONE COMPOUND, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL APPLICATION THEREOF | BEIJING INNOCARE PHARMA TECH CO., LTD. (CN) | 2021-07-22 | — | — | US | disclosed |
| EP-3805212-A1 | 3-OXAZOLINONE COMPOUND, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL APPLICATION THEREOF | Beijing InnoCare Pharma Tech Co., Ltd. (CN) | 2021-04-14 | — | — | EP | disclosed |
| EP-3805212-A1 | 3-OXAZOLINONE COMPOUND, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL APPLICATION THEREOF | Beijing InnoCare Pharma Tech Co., Ltd. (CN) | 2021-04-14 | — | — | EP | disclosed |
| US-20210046069-A1 | PENTAFLUOROSULFANYL-SUBSTITUTED AMIDE DERIVATIVES, PREPARATION METHODS THEREOF AND MEDICAL USES THEREOF | BEIJING INNOCARE PHARMA TECH CO., LTD. (CN) | 2021-02-18 | — | — | US | disclosed |
| US-20210046069-A1 | PENTAFLUOROSULFANYL-SUBSTITUTED AMIDE DERIVATIVES, PREPARATION METHODS THEREOF AND MEDICAL USES THEREOF | BEIJING INNOCARE PHARMA TECH CO., LTD. (CN) | 2021-02-18 | — | — | US | disclosed |
| CN-112334458-A | 3-indazolinone compound, preparation method and application thereof in medicine and pharmacology | 北京诺诚健华医药科技有限公司 | 2021-02-05 | — | — | CN | disclosed |
| EP-3747865-A1 | PENTAFLUOROSULFANYL-SUBSTITUTED AMIDE COMPOUND, PREPARATION METHOD THEREFOR, AND MEDICAL APPLICATION THEREOF | Beijing InnoCare Pharma Tech Co., Ltd. (CN) | 2020-12-09 | — | — | EP | disclosed |
| EP-3747865-A1 | PENTAFLUOROSULFANYL-SUBSTITUTED AMIDE COMPOUND, PREPARATION METHOD THEREFOR, AND MEDICAL APPLICATION THEREOF | Beijing InnoCare Pharma Tech Co., Ltd. (CN) | 2020-12-09 | — | — | EP | disclosed |
| CN-111630043-A | Compound containing ring, preparation method and application thereof in medicine | 四川科伦博泰生物医药股份有限公司 | 2020-09-04 | — | — | CN | disclosed |
| CN-111247119-A | Amidine and guanidine derivatives, preparation method and application thereof in medicines | 四川科伦博泰生物医药股份有限公司 | 2020-06-05 | — | — | CN | disclosed |
| WO-2019179369-A1 | RING-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR, AND MEDICAL APPLICATION THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-09-26 | — | — | WO | disclosed |
| WO-2019144781-A1 | PENTAFLUOROSULFANYL-SUBSTITUTED AMIDE COMPOUND, PREPARATION METHOD THEREFOR, AND MEDICAL APPLICATION THEREOF | 北京诺诚健华医药科技有限公司 | 2019-08-01 | — | — | WO | disclosed |
| WO-2019141095-A1 | AMIDINE AND GUANIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-07-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210221808-A1 | 3-OXAZOLINONE COMPOUND, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL APPLICATION THEREOF | IDO1, IDO2, INMT | ESR2 4775/4885PDE4A 1848/4885PDE4B 1689/4885 |
| US-20210046069-A1 | PENTAFLUOROSULFANYL-SUBSTITUTED AMIDE DERIVATIVES, PREPARATION METHODS THEREOF AND MEDICAL USES THEREOF | IDO1, IDO2, KYNU | ESR2 4813/4885PDE4A 2265/4885PDE4B 1862/4885 |
| US-11389445-B2 | Pentafluorosulfanyl-substituted amide derivatives, preparation methods thereof and medical uses thereof | IDO1, IDO2, KYNU | ESR2 4813/4885PDE4A 2265/4885PDE4B 1862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.