Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12323577 | 0.84 | PLK1 (0.44) | PLK1CYP4F2CYP4A11MAOBTARBP2 | |
| SCHEMBL779128 | 0.80 | TARBP2 (0.42) | TARBP2KDM4EAHRHSD17B10ALDH1A1 | |
| SCHEMBL2691856 | 0.77 | ALDH1A1 (0.51) | MAOBTARBP2KDM4EALDH1A1MAPT | |
| SCHEMBL26984654 | 0.75 | TARBP2 (0.45) | PLK1CYP4F2CYP4A11MAOBTARBP2 | |
| SCHEMBL2692459 | 0.74 | SMN1; SMN2 (0.49) | KDM4EHSD17B10ALDH1A1MAPTNPC1 | |
| SCHEMBL9750624 | 0.74 | KDM4E (0.45) | TARBP2KDM4EHSD17B10ALDH1A1MAPT | |
| SCHEMBL3532745 | 0.73 | NPC1 (0.40) | PLK1KDM4EHSD17B10ALDH1A1MAPT | |
| SCHEMBL3536411 | 0.72 | TARBP2 (0.62) | MAOBTARBP2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL23214404 | 0.71 | FBP1 (0.50) | KDM4EAHRHSD17B10ALDH1A1MAPT | |
| SCHEMBL23214485 | 0.71 | TARBP2 (0.40) | PLK1MAOBTARBP2KDM4EAHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019142053-A2 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2019-07-25 | — | — | WO | disclosed |
| WO-2019142053-A2 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2019-07-25 | — | — | WO | disclosed |