Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARBP2 | Q15633 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3416276 | 0.81 | ALDH1A1 (0.58) | ALDH1A1LMNAKDM4ENPC1MAPT | |
| SCHEMBL3274432 | 0.81 | MAPT (0.47) | TARBP2ALDH1A1LMNAKDM4ECYP1A2 | |
| SCHEMBL21177306 | 0.80 | PLK1 (0.43) | TARBP2ALDH1A1KDM4ECYP1A2NPC1 | |
| SCHEMBL9750624 | 0.79 | KDM4E (0.45) | TARBP2ALDH1A1KDM4ECYP1A2MAPT | |
| SCHEMBL11164366 | 0.79 | TARBP2 (0.42) | TARBP2ALDH1A1LMNAKDM4ECYP1A2 | |
| SCHEMBL781841 | 0.79 | FBP1 (0.56) | ALDH1A1LMNAKDM4ECYP1A2NPC1 | |
| SCHEMBL9750715 | 0.79 | CYP1A2 (0.41) | TARBP2ALDH1A1LMNAKDM4ECYP1A2 | |
| SCHEMBL25369787 | 0.77 | CYP1A2 (0.40) | TARBP2ALDH1A1LMNAKDM4ECYP1A2 | |
| SCHEMBL3822181 | 0.76 | FBP1 (0.41) | ALDH1A1LMNAKDM4ECYP1A2NPC1 | |
| SCHEMBL20378301 | 0.76 | ALDH1A1 (0.41) | TARBP2ALDH1A1LMNAKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0027020-B1 | 2-SUBSTITUTED-4-ALKYL OR TRIHALOALKYL-5-OXAZOLECARBOXYLIC ACID DERIVATIVES, THEIR USE AS SAFENING AGENTS AND HERBICIDAL COMPOSITIONS CONTAINING THEM | MONSANTO COMPANY (US) | 1983-04-13 | — | — | EP | claimed |
| US-4360678-A | PLANT SAFENING AGENT | MONSANTO COMPANY (US) | 1982-11-23 | — | — | US | claimed |
| EP-0027020-A1 | 2-Substituted-4-alkyl or trihaloalkyl-5-oxazolecarboxylic acid derivatives, their use as safening agents and herbicidal compositions containing them | MONSANTO COMPANY (US) | 1981-04-15 | — | — | EP | claimed |
| EP-4522606-A1 | INHIBITORS OF HUMAN RESPIRATORY SYNCYTIAL VIRUS AND METAPNEUMOVIRUS | Merck Sharp & Dohme LLC (US) | 2025-03-19 | — | — | EP | disclosed |
| US-20230365531-A1 | INHIBITORS OF HUMAN RESPIRATORY SYNCYTIAL VIRUS AND METAPNEUMO VIRUS | MERCK SHARP & DOHME LLC (US) | 2023-11-16 | — | — | US | disclosed |
| WO-2023220223-A1 | INHIBITORS OF HUMAN RESPIRATORY SYNCYTIAL VIRUS AND METAPNEUMOVIRUS | MERCK SHARP & DOHME LLC (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2019142053-A2 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2019-07-25 | — | — | WO | disclosed |
| WO-2019142053-A2 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2019-07-25 | — | — | WO | disclosed |
| US-9987255-B2 | 5,5-bicyclic oxazole orexin receptor antagonists | MERCK SHARP & DOHME CORP. (US) | 2018-06-05 | — | — | US | disclosed |
| US-20170368035-A1 | 5,5-Bicyclic Oxazole Orexin Receptor Antagonists | MERCK SHARP & DOHME LLC | 2017-12-28 | — | — | US | disclosed |
| US-20170152263-A1 | Substituted Indazole Compounds as IRAK4 Inhibitors | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2017-06-01 | — | — | US | disclosed |
| WO-2007146066-A2 | NOVEL PIPERAZINES, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF | CRITICAL THERAPEUTICS, INC. (US) | 2007-12-21 | — | — | WO | disclosed |
| US-6743814-B2 | REACTING 4-BROMO-1,1,2-TRIFLUORO-1-BUTENE WITH 2-MERCAPTO-OXAZOLE | NIHON BAYER AGROCHEM K.K. (JP) | 2004-06-01 | — | — | US | disclosed |
| US-20030109563-A1 | Combating nematodes characterized in that trifluorobutenes of the formula (I) are allowed to act on nematodes and/or their habitat. | NIHON BAYER AGROCHIM K.K. (JP) | 2003-06-12 | — | — | US | disclosed |
| EP-1263744-A1 | NEMATICIDAL TRIFLUOROBUTENES | NIHON BAYER AGROCHEM K.K. (JP) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001066529-A1 | NEMATICIDAL TRIFLUOROBUTENES | NIHON BAYER AGROCHEM K.K. (DE) | 2001-09-13 | — | — | WO | disclosed |
| EP-0027020-B1 | 2-SUBSTITUTED-4-ALKYL OR TRIHALOALKYL-5-OXAZOLECARBOXYLIC ACID DERIVATIVES, THEIR USE AS SAFENING AGENTS AND HERBICIDAL COMPOSITIONS CONTAINING THEM | MONSANTO COMPANY (US) | 1983-04-13 | — | — | EP | disclosed |
| US-4360678-A | PLANT SAFENING AGENT | MONSANTO COMPANY (US) | 1982-11-23 | — | — | US | disclosed |
| US-4303439-A | ANTIDOTES TO REDUCE HERBICIDAL INJURY | MONSANTO COMPANY (US) | 1981-12-01 | — | — | US | disclosed |
| EP-0027020-A1 | 2-Substituted-4-alkyl or trihaloalkyl-5-oxazolecarboxylic acid derivatives, their use as safening agents and herbicidal compositions containing them | MONSANTO COMPANY (US) | 1981-04-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030109563-A1 | Combating nematodes characterized in that trifluorobutenes of the formula (I) are allowed to act on nematodes and/or their habitat. | NAT1, CNR1, CTRL | TARBP2 3327/4885ALDH1A1 676/4885LMNA 2232/4885 |
| US-20230365531-A1 | INHIBITORS OF HUMAN RESPIRATORY SYNCYTIAL VIRUS AND METAPNEUMO VIRUS | METAP1, SARS1, RTF1 | TARBP2 402/4885ALDH1A1 4105/4885LMNA 2519/4885 |
| US-20170368035-A1 | 5,5-Bicyclic Oxazole Orexin Receptor Antagonists | HCRTR2, HCRTR1, NPY5R | TARBP2 4583/4885ALDH1A1 2185/4885LMNA 3853/4885 |
| US-20170152263-A1 | Substituted Indazole Compounds as IRAK4 Inhibitors | IRAK4, IRAK3, IRAK2 | TARBP2 1874/4885ALDH1A1 1980/4885LMNA 2416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.