Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 3/20 | 0.43 |
| ▸ | DCK | P27707 | 2/20 | 0.41 |
| ▸ | GPR6 | P46095 | 2/20 | 0.40 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.40 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21191758 | 1.00 | PDE10A (0.43) | PDE10ACHEK1CHEK2KDRDCK | |
| Hydrochloric Acid SCHEMBL21177938 | 0.99 | PDE10A (0.42) | PDE10ACHEK1CHEK2KDRDCK | |
| SCHEMBL21191757 | 0.89 | PDE10A (0.44) | PDE10ACHEK1CHEK2KDRDCK | |
| SCHEMBL21177943 | 0.85 | PDE10A (0.40) | PDE10ACHEK1CHEK2KDRDCK | |
| SCHEMBL21177698 | 0.81 | GPR119 (0.40) | PDE10AGPR6IKBKETBK1RET | |
| SCHEMBL21191756 | 0.80 | PDE10A (0.42) | PDE10ADCKGPR6RETPDE3B | |
| SCHEMBL21177705 | 0.80 | PDE10A (0.42) | PDE10ADCKGPR6RETPDE3B | |
| SCHEMBL21179336 | 0.78 | PDE10A (0.41) | PDE10ADCKGPR6RETPDE3B | |
| SCHEMBL21191943 | 0.78 | PDE10A (0.41) | PDE10ADCKGPR6RETPDE3B | |
| SCHEMBL21191891 | 0.78 | PDE10A (0.38) | PDE10ADCKGPR6RETCHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141957-A1 | N-PYRIMIDINYL HYDROXY PYRAZOLE DERIVATIVES AND USES THEREOF | CADO BIOTECHNOLOGY IVS (DK) | 2019-07-25 | — | — | WO | disclosed |