Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.40 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 7/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.38 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.38 |
| ▸ | GPR6 | P46095 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21177943 | 0.88 | PDE10A (0.40) | PDE10ARETTBK1IKBKEGPR6 | |
| SCHEMBL21191757 | 0.85 | PDE10A (0.44) | PDE10ARETTBK1IKBKEGPR6 | |
| SCHEMBL21177314 | 0.81 | PDE10A (0.43) | PDE10ARETTBK1IKBKEGPR6 | |
| SCHEMBL21191758 | 0.81 | PDE10A (0.43) | PDE10ARETTBK1IKBKEGPR6 | |
| Hydrochloric Acid SCHEMBL21177938 | 0.80 | PDE10A (0.42) | PDE10ARETTBK1IKBKEGPR6 | |
| SCHEMBL21191756 | 0.75 | PDE10A (0.42) | PDE10ARETGPR6 | |
| SCHEMBL21177705 | 0.75 | PDE10A (0.42) | PDE10ARETGPR6 | |
| SCHEMBL21191755 | 0.75 | GPR119 (0.55) | GPR119TBK1 | |
| SCHEMBL21191943 | 0.74 | PDE10A (0.41) | PDE10ARETGPR6 | |
| SCHEMBL21179336 | 0.74 | PDE10A (0.41) | PDE10ARETGPR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141957-A1 | N-PYRIMIDINYL HYDROXY PYRAZOLE DERIVATIVES AND USES THEREOF | CADO BIOTECHNOLOGY IVS (DK) | 2019-07-25 | — | — | WO | disclosed |