SCHEMBL21177632

SCHEMBL21177632

CCCOC(=O)C(C)[Si](OCC)(OCC)OCC

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.34
ALDH1A1 P00352 5/20 0.33
LMNA P02545 3/20 0.32
ESR1 P03372 1/20 0.32
CHRM1 P11229 1/20 0.32
TSHR P16473 1/20 0.32
SLC6A2 P23975 1/20 0.32
KDR P35968 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MAPT P10636 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
HSD17B10 Q99714 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22614816 0.89 ALDH1A1 (0.45) HCAR2ALDH1A1LMNAESR1TSHR
SCHEMBL21177899 0.87 NAAA (0.44) HCAR2ALDH1A1LMNATSHRNPSR1
SCHEMBL21177540 0.85 NAAA (0.47) HCAR2ALDH1A1LMNATSHRNPSR1
SCHEMBL21177529 0.85 NAAA (0.47) HCAR2ALDH1A1LMNATSHRNPSR1
SCHEMBL21179436 0.85 NAAA (0.47) HCAR2ALDH1A1LMNATSHRNPSR1
SCHEMBL8413238 0.85 ALDH1A1 (0.40) ALDH1A1LMNATSHRHSD17B10
SCHEMBL21177565 0.82 HCAR2 (0.33) HCAR2ALDH1A1LMNAESR1CHRM1
SCHEMBL22614788 0.82 HCAR2 (0.33) HCAR2ALDH1A1LMNAESR1CHRM1
SCHEMBL21182312 0.82 HCAR2 (0.35) HCAR2ALDH1A1LMNAESR1CHRM1
SCHEMBL10363666 0.79 SMN1; SMN2 (0.37) ALDH1A1LMNATSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11702574-B2 Adhesive silicone composition and an adhesive film or tape SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-07-18 US disclosed
US-20200347281-A1 ADHESIVE SILICONE COMPOSITION AND AN ADHESIVE FILM OR TAPE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-11-05 US disclosed
WO-2019142779-A1 SILICONE ADHESIVE COMPOSITION, ADHESIVE FILM, AND ADHESIVE TAPE 信越化学工業株式会社 2019-07-25 WO disclosed
CN-103172655-B Organosiloxane and its manufacture method containing anhydride group 信越化学工业株式会社 2017-10-17 CN disclosed
CN-102942585-B Succinic anhydride group containing cyclic organosiloxane, preparation thereof, organosiloxane composition and thermosetting resin composition 信越化学工业株式会社 2017-05-24 CN disclosed
CN-103131011-B Organosiloxane containing anhydride group and manufacture method thereof 信越化学工业株式会社 2016-12-21 CN disclosed
CN-103172655-A Organosiloxane containing acid anhydride group and method for preparing the same SHINETSU CHEMICAL CO 2013-06-26 CN disclosed
CN-103131011-A Organosiloxane containing anhydride groups and manufacturing method thereof SHINETSU CHEMICAL CO 2013-06-05 CN disclosed
CN-102942585-A Succinic anhydride group containing cyclic organosiloxane, preparation thereof, organosiloxane composition and thermosetting resin composition SHINETSU CHEMICAL CO 2013-02-27 CN disclosed