SCHEMBL21177899

SCHEMBL21177899

CCCCCOC(=O)C(C)[Si](OCC)(OCC)OCC

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.44
EPHX1 P07099 1/20 0.42
TSHR P16473 4/20 0.41
HCAR2 Q8TDS4 2/20 0.40
ALDH1A1 P00352 2/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPK1 P28482 1/20 0.39
RAD52 P43351 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
FAAH O00519 1/20 0.38
LMNA P02545 1/20 0.38
ATM Q13315 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21177540 0.98 NAAA (0.47) NAAAEPHX1TSHRHCAR2ALDH1A1
SCHEMBL21179436 0.98 NAAA (0.47) NAAAEPHX1TSHRHCAR2ALDH1A1
SCHEMBL21177529 0.98 NAAA (0.47) NAAAEPHX1TSHRHCAR2ALDH1A1
SCHEMBL22614816 0.95 ALDH1A1 (0.45) NAAAEPHX1TSHRHCAR2ALDH1A1
SCHEMBL21177632 0.87 HCAR2 (0.34) TSHRHCAR2ALDH1A1NPSR1LMNA
SCHEMBL21177515 0.84 NAAA (0.43) NAAAEPHX1TSHRHCAR2ALDH1A1
SCHEMBL21182325 0.84 NAAA (0.46) NAAAEPHX1TSHRHCAR2ALDH1A1
SCHEMBL21180358 0.83 NAAA (0.46) NAAAEPHX1TSHRHCAR2ALDH1A1
SCHEMBL21177498 0.83 NAAA (0.46) NAAAEPHX1TSHRHCAR2ALDH1A1
SCHEMBL28442884 0.83 NAAA (0.46) NAAAEPHX1TSHRHCAR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11702574-B2 Adhesive silicone composition and an adhesive film or tape SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-07-18 US disclosed
US-20200347281-A1 ADHESIVE SILICONE COMPOSITION AND AN ADHESIVE FILM OR TAPE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-11-05 US disclosed
WO-2019142779-A1 SILICONE ADHESIVE COMPOSITION, ADHESIVE FILM, AND ADHESIVE TAPE 信越化学工業株式会社 2019-07-25 WO disclosed
CN-103172655-B Organosiloxane and its manufacture method containing anhydride group 信越化学工业株式会社 2017-10-17 CN disclosed
CN-102942585-B Succinic anhydride group containing cyclic organosiloxane, preparation thereof, organosiloxane composition and thermosetting resin composition 信越化学工业株式会社 2017-05-24 CN disclosed
CN-103131011-B Organosiloxane containing anhydride group and manufacture method thereof 信越化学工业株式会社 2016-12-21 CN disclosed
CN-103172655-A Organosiloxane containing acid anhydride group and method for preparing the same SHINETSU CHEMICAL CO 2013-06-26 CN disclosed
CN-103131011-A Organosiloxane containing anhydride groups and manufacturing method thereof SHINETSU CHEMICAL CO 2013-06-05 CN disclosed
CN-102942585-A Succinic anhydride group containing cyclic organosiloxane, preparation thereof, organosiloxane composition and thermosetting resin composition SHINETSU CHEMICAL CO 2013-02-27 CN disclosed