SCHEMBL21177751

SCHEMBL21177751

CCCCOC(=O)C(C)[SiH2]OC(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
ATM Q13315 1/20 0.40
TSHR P16473 3/20 0.38
HPGD P15428 2/20 0.38
HCAR2 Q8TDS4 1/20 0.36
NAAA Q02083 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35
MAPT P10636 2/20 0.35
ESR1 P03372 3/20 0.33
HSD17B10 Q99714 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
EPHX1 P07099 1/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21177514 0.95 NAAA (0.42) ALDH1A1TSHRHCAR2NAAANPSR1
SCHEMBL28442886 0.93 NAAA (0.44) ALDH1A1TSHRHCAR2NAAANPSR1
SCHEMBL21177761 0.93 NAAA (0.44) ALDH1A1TSHRHCAR2NAAANPSR1
SCHEMBL21177497 0.93 NAAA (0.44) ALDH1A1TSHRHCAR2NAAANPSR1
SCHEMBL22614787 0.89 HCAR2 (0.32) ALDH1A1TSHRHCAR2TDP1RAB9A
SCHEMBL21177901 0.82 ALOX15 (0.38) ALDH1A1TSHRHPGDSMN1; SMN2HSD17B10
SCHEMBL21179455 0.79 ALDH1A1 (0.45) ALDH1A1ATMTSHRHPGDHCAR2
SCHEMBL22614864 0.75 NAAA (0.46) ALDH1A1TSHRHCAR2NAAANPSR1
SCHEMBL3678999 0.75 ALDH1A1 (0.58) ALDH1A1ATMTSHRHPGDHCAR2
SCHEMBL22614818 0.74 NAAA (0.48) ALDH1A1TSHRHCAR2NAAANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11702574-B2 Adhesive silicone composition and an adhesive film or tape SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-07-18 US disclosed
CN-111601866-B Silicone adhesive composition, cured product, adhesive film, and adhesive tape 信越化学工业株式会社 2022-09-06 CN disclosed
US-20200347281-A1 ADHESIVE SILICONE COMPOSITION AND AN ADHESIVE FILM OR TAPE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-11-05 US disclosed
CN-111601866-A Silicone adhesive composition, adhesive film, and adhesive tape 信越化学工业株式会社 2020-08-28 CN disclosed
WO-2019142779-A1 SILICONE ADHESIVE COMPOSITION, ADHESIVE FILM, AND ADHESIVE TAPE 信越化学工業株式会社 2019-07-25 WO disclosed