Trolamine

Trolamine

SCHEMBL21177786

NCC(O)c1ccccc1.OCCN(CCO)CCO

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.47
HTR3A P46098 1/20 0.47
TSHR P16473 1/20 0.47
NFKB1 P19838 1/20 0.47
HIF1A Q16665 1/20 0.47
AOC3 Q16853 5/20 0.46
KDM4E B2RXH2 3/20 0.46
ALOX15 P16050 1/20 0.46
APEX1 P27695 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
LMNA P02545 1/20 0.44
HTR2A P28223 1/20 0.43
SLC6A2 P23975 2/20 0.43
SLC6A4 P31645 2/20 0.43
SLC6A3 Q01959 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.42
PNMT P11086 1/20 0.41
GABBR2 O75899 1/20 0.40
GABBR1 Q9UBS5 1/20 0.40
BCAT2 O15382 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Monoethanolamine SCHEMBL9507297 0.84 TAAR1 (0.54) TAAR1HTR3ATSHRNFKB1HIF1A
SCHEMBL175554 0.84 TAAR1 (0.62) TAAR1HTR3ATSHRNFKB1HIF1A
SCHEMBL147501 0.84 TAAR1 (0.62) TAAR1HTR3ATSHRNFKB1HIF1A
SCHEMBL2021 0.84 TAAR1 (0.62) TAAR1HTR3ATSHRNFKB1HIF1A
Hydrochloric Acid SCHEMBL7153880 0.82 KDM4E (0.64) TAAR1HTR3ATSHRNFKB1HIF1A
Hydrochloric Acid SCHEMBL29175850 0.82 KDM4E (0.64) TAAR1HTR3ATSHRNFKB1HIF1A
Ammonia Solution, Strong SCHEMBL27544022 0.82 TAAR1 (0.60) TAAR1HTR3ATSHRNFKB1HIF1A
Hydrochloric Acid SCHEMBL8178381 0.82 KDM4E (0.64) TAAR1HTR3ATSHRNFKB1HIF1A
Bromide SCHEMBL29131747 0.82 TAAR1 (0.60) TAAR1HTR3ATSHRNFKB1HIF1A
SCHEMBL9641990 0.81 KDM4E (0.54) TAAR1TSHRAOC3KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019142854-A1 SYNTHESIS METHOD FOR BORONIC ACID ESTER COMPOUND, AND SODIUM SALT OF BORONIC ACID ESTER COMPOUND AND SYNTHESIS METHOD THEREFOR 株式会社神鋼環境ソリューション 2019-07-25 WO disclosed