SCHEMBL2021

SCHEMBL2021

NCC(O)c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 6/20 0.62
HTR3A P46098 1/20 0.62
TSHR P16473 1/20 0.62
NFKB1 P19838 1/20 0.62
HIF1A Q16665 1/20 0.62
KDM4E B2RXH2 2/20 0.60
APEX1 P27695 2/20 0.60
TDP1 Q9NUW8 2/20 0.60
ALOX15 P16050 1/20 0.60
HTR2A P28223 1/20 0.59
LMNA P02545 2/20 0.58
AOC3 Q16853 5/20 0.58
L3MBTL1 Q9Y468 1/20 0.56
SLC6A2 P23975 1/20 0.56
SLC6A4 P31645 1/20 0.56
SLC6A3 Q01959 1/20 0.56
PNMT P11086 1/20 0.52
MEN1 O00255 1/20 0.50
ADRB2 P07550 1/20 0.50
ADRB1 P08588 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL147501 1.00 TAAR1 (0.62) TAAR1HTR3ATSHRNFKB1HIF1A
SCHEMBL175554 1.00 TAAR1 (0.62) TAAR1HTR3ATSHRNFKB1HIF1A
Hydrochloric Acid SCHEMBL29175850 0.97 KDM4E (0.64) TAAR1HTR3ATSHRNFKB1HIF1A
Hydrochloric Acid SCHEMBL7153880 0.97 KDM4E (0.64) TAAR1HTR3ATSHRNFKB1HIF1A
Ammonia Solution, Strong SCHEMBL27544022 0.97 TAAR1 (0.60) TAAR1HTR3ATSHRNFKB1HIF1A
Hydrochloric Acid SCHEMBL8178381 0.97 KDM4E (0.64) TAAR1HTR3ATSHRNFKB1HIF1A
Bromide SCHEMBL29131747 0.97 TAAR1 (0.60) TAAR1HTR3ATSHRNFKB1HIF1A
SCHEMBL8339683 0.91 TAAR1 (0.56) TAAR1HTR3ATSHRNFKB1HIF1A
Monoethanolamine SCHEMBL9507297 0.91 TAAR1 (0.54) TAAR1HTR3ATSHRNFKB1HIF1A
Alcohol SCHEMBL1532267 0.91 LMNA (0.61) TAAR1HTR3ATSHRNFKB1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7763 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
US-20260138972-A1 PREPARATION METHOD AND CHIRAL SIEVING APPLICATION OF NOVEL 12-CROWN-4 COVALENT ORGANIC FRAMEWORKS CHONGQING UNIV OF ARTS AND SCIENCES (CN) 2026-05-21 US claimed
US-12435280-B2 Crude oil demulsifier compositions and uses thereof ECOLAB USA INC. (US) 2025-10-07 US claimed
EP-3911795-B1 METHOD OF STRENGTHENING NON-KERATINOUS FIBERS, AND USES THEREOF ISP INVESTMENTS LLC (US) 2025-10-01 EP claimed
CN-120118480-A Degradable epoxy resin composite material with adjustable curing speed and preparation and moderate full recycling methods thereof 哈尔滨工业大学 2025-06-10 CN claimed
CN-120082162-A Flame-retardant modified ABS plastic and preparation method thereof 东莞市精佰技术有限公司 2025-06-03 CN claimed
CN-120054619-A Catalyst for preparing chiral beta-amino alcohol and method for preparing chiral beta-amino alcohol using the same 北京旭阳科技有限公司 2025-05-30 CN claimed
CN-120025542-A Non-isocyanate polyurethane and multicomponent selective synthesis method thereof 华南理工大学 2025-05-23 CN claimed
CN-119663650-B Production process of antistatic nylon fabric 安徽金弘润新材料科技有限公司 2025-05-13 CN claimed
WO-2025073830-A1 STABLE MODIFIED POLYMER POLYOL DISPERSIONS REPSOL, S.A. (ES) 2025-04-10 WO claimed
EP-0008715-B1 PHENYLETHANOLAMINES FOR USE IN COMBATTING INFLAMMATORY CONDITIONS Dr. Karl Thomae GmbH (DE) 1981-11-25 EP claimed
US-4276297-A ANTIULCER AGENTS PFIZER INC. (US) 1981-06-30 US claimed
US-4253918-A FOR PAPER SUBSTRATES PFIZER INC. (US) 1981-03-03 US claimed
EP-0019411-A1 1-Phenyl-2-aminoethanol derivatives, processes for their manufacture and pharmaceutical compositions thereof IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1980-11-26 EP claimed
US-4217305-A HYPOTENSIVE AGENTS, ADRENERGIC BLOCKING AGENTS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1980-08-12 US claimed
EP-0006298-A1 Anti-inflammatory 1-phenyl-2-aminoethanol derivatives, pharmaceutical compositions thereof for topical use, and processes for their manufacture IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1980-01-09 EP claimed
EP-0000809-A1 Anti-inflammatory 1-phenylethanolamine derivatives, pharmaceutical compositions thereof and processes for their manufacture IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1979-02-21 EP claimed
US-3972839-A ALKANOLAMINE, ALKALI METAL HYDROXIDE OXY METAL INDUSTRIES CORPORATION (US) 1976-08-03 US claimed
US-3971834-A ULTRAVIOLET CURABLE SHELL OIL COMPANY (US) 1976-07-27 US claimed
US-3930948-A ENZYMATIC METHOD FOR PRODUCING AROMATIC ETHYLAMINES AJINOMOTO CO., INC. (JA) 1976-01-06 US claimed