Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.62 |
| ▸ | HTR3A | P46098 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | APEX1 | P27695 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | PNMT | P11086 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL147501 | 1.00 | TAAR1 (0.62) | TAAR1HTR3ATSHRNFKB1HIF1A | |
| SCHEMBL2021 | 1.00 | TAAR1 (0.62) | TAAR1HTR3ATSHRNFKB1HIF1A | |
| Hydrochloric Acid SCHEMBL8178381 | 0.97 | KDM4E (0.64) | TAAR1HTR3ATSHRNFKB1HIF1A | |
| Hydrochloric Acid SCHEMBL7153880 | 0.97 | KDM4E (0.64) | TAAR1HTR3ATSHRNFKB1HIF1A | |
| Ammonia Solution, Strong SCHEMBL27544022 | 0.97 | TAAR1 (0.60) | TAAR1HTR3ATSHRNFKB1HIF1A | |
| Hydrochloric Acid SCHEMBL29175850 | 0.97 | KDM4E (0.64) | TAAR1HTR3ATSHRNFKB1HIF1A | |
| Bromide SCHEMBL29131747 | 0.97 | TAAR1 (0.60) | TAAR1HTR3ATSHRNFKB1HIF1A | |
| SCHEMBL8339683 | 0.91 | TAAR1 (0.56) | TAAR1HTR3ATSHRNFKB1HIF1A | |
| Monoethanolamine SCHEMBL9507297 | 0.91 | TAAR1 (0.54) | TAAR1HTR3ATSHRNFKB1HIF1A | |
| Alcohol SCHEMBL1532267 | 0.91 | LMNA (0.61) | TAAR1HTR3ATSHRNFKB1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250135005-A1 | PROCESSES FOR PREPARING FUNCTIONALIZED CYCLOOCTENES | TAMBO INC (US) | 2025-05-01 | — | — | US | claimed |
| WO-2024169071-A1 | METHOD FOR PREPARING SACUBITRIL COMPOUND BY MEANS OF ASYMMETRIC CATALYTIC HYDROGENATION | 瑞博(苏州)制药有限公司 | 2024-08-22 | — | — | WO | claimed |
| CN-115974634-B | Method for preparing Sha Kuba curved compound by asymmetric catalytic hydrogenation | 瑞博(苏州)制药有限公司 | 2023-11-28 | — | — | CN | claimed |
| CN-111718362-B | Preparation and application of chiral zinc complex | 合肥工业大学 | 2023-06-20 | — | — | CN | claimed |
| CN-115974634-A | Method for preparing Shakubatu compound by asymmetric catalytic hydrogenation | 瑞博(苏州)制药有限公司 | 2023-04-18 | — | — | CN | claimed |
| US-20230048657-A1 | PROCESS FOR THE PREPARATION OF (9S)-2-BROMO-9-(2,3,4-TRIFLUOROPHENYL)-6,7,8,9-TETRAHYDRO-5H-[1,2,4]TRIAZOLO[1,5-A]AZEPINE | HOFFMANN-LA ROCHE INC. (US) | 2023-02-16 | — | — | US | claimed |
| EP-4065581-A1 | PROCESS FOR THE PREPARATION (9S)-2-BROMO-9-(2,3,4-TRIFLUOROPHENYL)-6,7,8,9-TETRAHYDRO-5H-[1,2,4]TRIAZOLO[1,5-A]AZEPINE | F. Hoffmann-La Roche AG (CH) | 2022-10-05 | — | — | EP | claimed |
| CN-114787163-A | Process for preparing (9S) -2-bromo-9- (2,3, 4-trifluorophenyl) -6,7,8, 9-tetrahydro-5H- [1,2,4] triazolo [1,5-a ] azepine | 豪夫迈·罗氏有限公司 | 2022-07-22 | — | — | CN | claimed |
| CN-112280761-B | Recombinant transaminase, mutant of recombinant transaminase and application of mutant | 清华大学 | 2022-04-12 | — | — | CN | claimed |
| US-20220033408-A1 | PROCESS FOR PREPARING SPIRO DERIVATIVES | JOHNSON MATTHEY PLC (GB) | 2022-02-03 | — | — | US | claimed |
| EP-0654534-B1 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEM (JP) | 2000-03-01 | — | — | EP | claimed |
| WO-1999044985-A2 | SYNTHESIS OF CHIRAL β-AMINO ACIDS | G.D. SEARLE & CO. (US) | 1999-09-10 | — | — | WO | claimed |
| EP-0939134-A1 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-09-01 | — | — | EP | claimed |
| US-5932742-A | CHEMICAL INTERMEDIATE TO ACTIVE ANTITUMOR AGENT | DONG WHA PHARM. IND. CO., LTD. (KR) | 1999-08-03 | — | — | US | claimed |
| EP-0912495-A1 | ASYMETRIC SYNTHESIS OF CHIRAL BETA-AMINO ACIDS | G.D. SEARLE & CO. (US) | 1999-05-06 | — | — | EP | claimed |
| US-5840961-A | Asymmetric synthesis of chiral beta-amiNo acids | G. D. SEARLE & CO. (US) | 1998-11-24 | — | — | US | claimed |
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | claimed |
| WO-1998002410-A1 | ASYMETRIC SYNTHESIS OF CHIRAL BETA-AMINO ACIDS | G.D. SEARLE & CO. (US) | 1998-01-22 | — | — | WO | claimed |
| EP-0654534-A2 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1995-05-24 | — | — | EP | claimed |
| EP-0005848-B1 | N-ALKYLATED AMINOALCOHOLS AND THEIR SALTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1981-12-30 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230048657-A1 | PROCESS FOR THE PREPARATION OF (9S)-2-BROMO-9-(2,3,4-TRIFLUOROPHENYL)-6,7,8,9-TETRAHYDRO-5H-[1,2,4]TRIAZOLO[1,5-A]AZEPINE | APP, PSEN1, PSEN2 | TAAR1 2149/4885HTR3A 12/4885TSHR 4050/4885 |
| US-20220033408-A1 | PROCESS FOR PREPARING SPIRO DERIVATIVES | DHPS, TALDO1, FASTKD5 | TAAR1 2043/4885HTR3A 2126/4885TSHR 2820/4885 |
| US-20250135005-A1 | PROCESSES FOR PREPARING FUNCTIONALIZED CYCLOOCTENES | PPOX, SCO2, CYCS | TAAR1 1065/4885HTR3A 2701/4885TSHR 3738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.