Sugi Predict

Sugi Predict / Compounds / SCHEMBL147501

SCHEMBL147501

SCHEMBL147501

NC[C@H](O)c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TAAR1 Q96RJ0 6/20 0.62
▸ HTR3A P46098 1/20 0.62
▸ TSHR P16473 1/20 0.62
▸ NFKB1 P19838 1/20 0.62
▸ HIF1A Q16665 1/20 0.62
▸ KDM4E B2RXH2 2/20 0.60
▸ APEX1 P27695 2/20 0.60
▸ TDP1 Q9NUW8 2/20 0.60
▸ ALOX15 P16050 1/20 0.60
▸ HTR2A P28223 1/20 0.59
▸ LMNA P02545 2/20 0.58
▸ AOC3 Q16853 5/20 0.58
▸ L3MBTL1 Q9Y468 1/20 0.56
▸ SLC6A2 P23975 1/20 0.56
▸ SLC6A4 P31645 1/20 0.56
▸ SLC6A3 Q01959 1/20 0.56
▸ PNMT P11086 1/20 0.52
▸ MEN1 O00255 1/20 0.50
▸ ADRB2 P07550 1/20 0.50
▸ ADRB1 P08588 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2021 1.00 TAAR1 (0.62) TAAR1HTR3ATSHRNFKB1HIF1A
SCHEMBL175554 1.00 TAAR1 (0.62) TAAR1HTR3ATSHRNFKB1HIF1A
Hydrochloric Acid SCHEMBL29175850 0.97 KDM4E (0.64) TAAR1HTR3ATSHRNFKB1HIF1A
Hydrochloric Acid SCHEMBL7153880 0.97 KDM4E (0.64) TAAR1HTR3ATSHRNFKB1HIF1A
Ammonia Solution, Strong SCHEMBL27544022 0.97 TAAR1 (0.60) TAAR1HTR3ATSHRNFKB1HIF1A
Hydrochloric Acid SCHEMBL8178381 0.97 KDM4E (0.64) TAAR1HTR3ATSHRNFKB1HIF1A
Bromide SCHEMBL29131747 0.97 TAAR1 (0.60) TAAR1HTR3ATSHRNFKB1HIF1A
SCHEMBL8339683 0.91 TAAR1 (0.56) TAAR1HTR3ATSHRNFKB1HIF1A
Monoethanolamine SCHEMBL9507297 0.91 TAAR1 (0.54) TAAR1HTR3ATSHRNFKB1HIF1A
Alcohol SCHEMBL1532267 0.91 LMNA (0.61) TAAR1HTR3ATSHRNFKB1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1366 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119751515-A Chiral spiral double-iron complex, preparation method and anti-tumor application thereof 首都医科大学 2025-04-04 — — CN claimed
EP-3694864-B1 BORONIC ACID DERIVATIVES AND SYNTHESIS THEREOF QPEX BIOPHARMA INC (US) 2025-03-05 — — EP claimed
CN-117756820-A Preparation method of levamisole hydrochloride 安徽英特美科技有限公司 2024-03-26 — — CN claimed
CN-109563085-B Piperidine CXCR7 receptor modulators 爱杜西亚药品有限公司 2022-08-09 — — CN claimed
CN-109651290-B Preparation method of mirabegron 安徽省庆云医药股份有限公司 2022-04-01 — — CN claimed
US-11286270-B2 Boronic acid derivatives and synthesis thereof QPEX BIOPHARMA, INC. (US) 2022-03-29 — — US claimed
EP-3490986-B1 PIPERIDINE CXCR7 RECEPTOR MODULATORS IDORSIA PHARMACEUTICALS LTD (CH) 2021-11-24 — — EP claimed
US-20200407373-A1 BORONIC ACID DERIVATIVES AND SYNTHESIS THEREOF QPEX BIOPHARMA, INC. 2020-12-31 — — US claimed
CN-111841537-A 3D (three-dimensional) mesh Cu-based catalyst and preparation method and application thereof 昆山诺梵生物科技有限公司 2020-10-30 — — CN claimed
CN-108059382-B Concrete glue reducing agent and preparation method thereof 武汉新绿博恩科技有限公司 2020-09-08 — — CN claimed
US-5629200-A MICROORGANISM DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1997-05-13 — — US claimed
WO-1997002236-A1 PROCESS FOR PRODUCING β-AMINO-α-HYDROXYCARBOXYLIC ACIDS AND DERIVATIVES THEREOF DEGUSSA AKTIENGESELLSCHAFT (DE) 1997-01-23 — — WO claimed
EP-0751224-A1 PROCESS FOR PRODUCING (R)-2-AMINO-1-PHENYLETHANOL OR HALOGENATED DERIVATIVE THEREOF, PROCESS FOR PRODUCING OPTICALLY ACTIVE PHENYLSERINE OR HALOGENATED DERIVATIVE THEREOF, AND NOVEL COMPOUND 3-(3-CHLOROPHENYL)SERINE DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1997-01-02 — — EP claimed
EP-0627397-B1 Optically active 1-phenyl-2-substituted propane derivatives and methods of producing the same DAICEL CHEM (JP) 1997-01-02 — — EP claimed
US-5523469-A REACTING ALKALI METAL SULFITE ON 1-(1-BROMOETHYL)-3-NITROBENZENE; CONVERSION TO POTASSIUM SALT; CONVERSION TO BENZYLQUINIUM SALT; THEN QUATERNIZATION RHONE-POULENC RORER S.A. (FR) 1996-06-04 — — US claimed
EP-0659175-A1 OPTICALLY ACTIVE ALKYLAMMONIUM (AMINO-3 PHENYL)-1 ETHANESULFONATE DERIVATIVES, PREPARATION AND USE THEREOF. RHONE POULENC RORER SA (FR) 1995-06-28 — — EP claimed
EP-0654534-A2 Processes for producing optically active 2-amino-1-phenylethanol derivatives DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1995-05-24 — — EP claimed
EP-0627397-A1 Optically active 1-phenyl-2-substituted propane derivatives and methods of producing the same DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1994-12-07 — — EP claimed
WO-1994006760-A1 OPTICALLY ACTIVE ALKYLAMMONIUM (AMINO-3 PHENYL)-1 ETHANESULFONATE DERIVATIVES, PREPARATION AND USE THEREOF RHONE-POULENC RORER S.A. (FR) 1994-03-31 — — WO claimed
EP-0005848-B1 N-ALKYLATED AMINOALCOHOLS AND THEIR SALTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM CIBA-GEIGY AG (CH) 1981-12-30 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200407373-A1 BORONIC ACID DERIVATIVES AND SYNTHESIS THEREOF BTD, BLVRB, BLK TAAR1 4656/4885HTR3A 4710/4885TSHR 3719/4885
US-11286270-B2 Boronic acid derivatives and synthesis thereof BTD, BLVRB, BLK TAAR1 4656/4885HTR3A 4710/4885TSHR 3719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.