Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 7/20 | 0.46 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.46 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6481541 | 1.00 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3KCNA5KCNJ5 | |
| SCHEMBL30663811 | 1.00 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3KCNA5KCNJ5 | |
| SCHEMBL1856673 | 0.85 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3KCNA5KCNJ5 | |
| SCHEMBL7306898 | 0.85 | KDM4E (0.49) | SLC6A2SLC6A4SLC6A3KCNA5KCNJ5 | |
| SCHEMBL30910020 | 0.84 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3KCNA5KCNJ5 | |
| SCHEMBL31744336 | 0.83 | KCNA5 (0.52) | SLC6A2SLC6A4SLC6A3KCNA5KCNJ5 | |
| SCHEMBL506917 | 0.83 | KCNA5 (0.52) | SLC6A2SLC6A4SLC6A3KCNA5KCNJ5 | |
| SCHEMBL7268370 | 0.83 | KCNA5 (0.52) | SLC6A2SLC6A4SLC6A3KCNA5KCNJ5 | |
| SCHEMBL29767197 | 0.83 | KCNA5 (0.52) | SLC6A2SLC6A4SLC6A3KCNA5KCNJ5 | |
| SCHEMBL6575099 | 0.82 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3KCNA5KCNJ5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250228865-A1 | COMPOUNDS FOR ENHANCING READ THROUGH OF GENES CONTAINING PREMATURE TERMINATION CODONS AND METHODS FOR MAKING AND USING THE SAME | SANOFI US SERVICES INC. (US) | 2025-07-17 | — | — | US | disclosed |
| US-20240294512-A1 | HYDROXY AND (HALO)ALKOXY SUBSTITUTED TETRAHYDROFURANS AS MODULATORS OF SODIUM CHANNELS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2024-09-05 | — | — | US | disclosed |
| EP-3388486-B1 | A CROSSLINKABLE COMPOSITION AND METHOD OF PRODUCING THE SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2021-06-02 | — | — | EP | disclosed |
| US-8993773-B2 | Process to prepare pioglitazone via several novel intermediates | CADILA HEALTHCARE LIMITED (IN) | 2015-03-31 | — | — | US | disclosed |
| EP-1963315-B1 | ENZYME INHIBITORS | CANCER REC TECH LTD (GB) | 2014-10-08 | — | — | EP | disclosed |
| US-20140088127-A1 | NOVEL PROCESS TO PREPARE PIOGLITAZONE VIA SEVERAL NOVEL INTERMEDIATES | CADILA HEALTHCARE LIMITED (IN) | 2014-03-27 | — | — | US | disclosed |
| US-8445685-B2 | Process to prepare pioglitazone via several novel intermediates | CADILA HEALTHCARE LIMITED (IN) | 2013-05-21 | — | — | US | disclosed |
| US-8173816-B2 | Process to prepare pioglitazone via several novel intermediates | CADILA HEALTHCARE LIMITED (IN) | 2012-05-08 | — | — | US | disclosed |
| US-20120077848-A1 | NOVEL PROCESS TO PREPARE PIOGLITAZONE VIA SEVERAL NOVEL INTERMEDIATES | CADILA HEALTHCARE LIMITED (IN) | 2012-03-29 | — | — | US | disclosed |
| US-8088761-B2 | Enzyme inhibitors | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2012-01-03 | — | — | US | disclosed |
| EP-1406605-A1 | CARBAMATES OF 2-HETEROCYCLIC-1,2-ETHANEDIOLS | SK Corporation (KR) | 2004-04-14 | — | — | EP | disclosed |
| US-20030078235-A1 | Carbamates of 2-heterocyclic-1,2-ethanediols | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2003-04-24 | — | — | US | disclosed |
| US-6506943-B1 | Reacting 1,2-diol with oxygen in presence of organic ruthenium complex as catalytic component supported on carrier to oxidatively cleave bond between two carbon atoms bearing hydroxyl groups and yield corresponding aldehyde | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2003-01-14 | — | — | US | disclosed |
| WO-2003000247-A1 | CARBAMATES OF 2-HETEROCYCLIC-1,2-ETHANEDIOLS | SK CORPORATION (KR) | 2003-01-03 | — | — | WO | disclosed |
| CN-1296468-A | method for producing aldehyde | DAICEL CHEMICA IND LTD (JP) | 2001-05-23 | — | — | CN | disclosed |
| EP-1078907-A1 | PROCESS FOR PRODUCING ALDEHYDES | Daicel Chemical Industries, Ltd. (JP) | 2001-02-28 | — | — | EP | disclosed |
| EP-0578194-B1 | Process for producing phenol and methyl ethyl ketone | SUMITOMO CHEMICAL CO (JP) | 1998-02-04 | — | — | EP | disclosed |
| US-5304684-A | Oxidizing sec-butylbenzene to hydroperoxide, concentrating, decomposing, neutralizing, distilling, washing | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| EP-0578194-A2 | Process for producing phenol and methyl ethyl ketone | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-01-12 | — | — | EP | disclosed |
| US-4111917-A | POLYURETHANES | W. R. GRACE & CO. (US) | 1978-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240294512-A1 | HYDROXY AND (HALO)ALKOXY SUBSTITUTED TETRAHYDROFURANS AS MODULATORS OF SODIUM CHANNELS | TRPV1, NHERF1, HCN4 | SLC6A2 182/4885SLC6A4 178/4885SLC6A3 259/4885 |
| US-20140088127-A1 | NOVEL PROCESS TO PREPARE PIOGLITAZONE VIA SEVERAL NOVEL INTERMEDIATES | PPARD, PPARG, PPARA | SLC6A2 3856/4885SLC6A4 2260/4885SLC6A3 2730/4885 |
| US-20120077848-A1 | NOVEL PROCESS TO PREPARE PIOGLITAZONE VIA SEVERAL NOVEL INTERMEDIATES | PPARD, PPARG, PPARA | SLC6A2 3856/4885SLC6A4 2260/4885SLC6A3 2730/4885 |
| US-20250228865-A1 | COMPOUNDS FOR ENHANCING READ THROUGH OF GENES CONTAINING PREMATURE TERMINATION CODONS AND METHODS FOR MAKING AND USING THE SAME | UPF1, NUDT21, RNGTT | SLC6A2 2609/4885SLC6A4 1941/4885SLC6A3 2073/4885 |
| US-20030078235-A1 | Carbamates of 2-heterocyclic-1,2-ethanediols | CNR2, CNR1, GRIN2C | SLC6A2 1992/4885SLC6A4 2797/4885SLC6A3 1090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.