Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 6/20 | 0.38 |
| ▸ | LPL | P06858 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21179831 | 0.87 | PRMT5 (0.41) | HIF1APRMT5WDR77CA1CA2 | |
| SCHEMBL18497263 | 0.86 | ROCK1 (0.44) | HIF1APRMT5WDR77CA1CA2 | |
| SCHEMBL21179836 | 0.86 | HIF1A (0.40) | HIF1APRMT5WDR77CA1CA2 | |
| SCHEMBL18989327 | 0.85 | PRMT5 (0.47) | HIF1ASMN1; SMN2PRMT5WDR77CA1 | |
| SCHEMBL21179832 | 0.84 | POLB (0.39) | HIF1APRMT5WDR77CA1CA2 | |
| SCHEMBL21236362 | 0.82 | LIPG (0.50) | HIF1ACA1CA2CA9LIPG | |
| SCHEMBL16881568 | 0.80 | CA1 (0.57) | HIF1ACA1CA2CA9LIPG | |
| SCHEMBL16794462 | 0.77 | NPC1 (0.43) | HIF1APRMT5WDR77CA1CA2 | |
| SCHEMBL13568196 | 0.76 | HIF1A (0.43) | HIF1APRMT5WDR77CA1CA2 | |
| SCHEMBL12502664 | 0.76 | HIF1A (0.48) | HIF1APRMT5WDR77CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10357036-B2 | Compounds for controlling arthropods | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10357036-B2 | Compounds for controlling arthropods | DDT, ACHE, NISCH | HIF1A 2130/4885SMN1; SMN2 2558/4885PRMT5 2797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.