Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21179840 | 0.87 | EPHX2 (0.44) | KMT2AALDH1A1EPHX2 | |
| SCHEMBL21179839 | 0.87 | ROCK1 (0.44) | POLBKMT2AROCK1HPGDKDM4E | |
| SCHEMBL21179835 | 0.84 | HIF1A (0.42) | PRMT5WDR77ROCK1HIF1ACA1 | |
| SCHEMBL21179831 | 0.84 | PRMT5 (0.41) | PRMT5WDR77ROCK1HIF1ACA1 | |
| SCHEMBL18989327 | 0.81 | PRMT5 (0.47) | PRMT5WDR77ROCK1HIF1ACA1 | |
| SCHEMBL3212986 | 0.81 | CA1 (0.54) | KMT2AHPGDKDM4EALDH1A1ALOX15 | |
| SCHEMBL553260 | 0.80 | LIPG (0.48) | POLBKMT2AHPGDKDM4EALDH1A1 | |
| SCHEMBL15739827 | 0.77 | NPC1 (0.45) | KMT2AHPGDHIF1AKDM4EALDH1A1 | |
| SCHEMBL21236362 | 0.76 | LIPG (0.50) | ROCK1HIF1ACA1CA2CA9 | |
| SCHEMBL552268 | 0.75 | ALDH1A1 (0.51) | KMT2AHPGDALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10357036-B2 | Compounds for controlling arthropods | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10357036-B2 | Compounds for controlling arthropods | DDT, ACHE, NISCH | POLB 4804/4885KMT2A 1510/4885PRMT5 2797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.