Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 7/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19428590 | 0.81 | FABP5 (0.41) | PDE5AL3MBTL1ALDH1A1KDM4EGLA | |
| SCHEMBL14649976 | 0.81 | FABP5 (0.41) | PDE5AL3MBTL1ALDH1A1KDM4EGLA | |
| SCHEMBL14653133 | 0.78 | KDM4E (0.33) | PDE5AFFAR2L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL12643732 | 0.78 | KDM4E (0.33) | PDE5AFFAR2L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL2039074 | 0.73 | ALDH1A1 (0.43) | PDE5AFFAR2L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL2039076 | 0.73 | ALDH1A1 (0.43) | PDE5AFFAR2L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL29788206 | 0.73 | ALDH1A1 (0.43) | PDE5AFFAR2L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL29788153 | 0.68 | HSD17B10 (0.41) | PDE5AFFAR2L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL2040425 | 0.68 | HSD17B10 (0.41) | PDE5AFFAR2L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL2040422 | 0.68 | HSD17B10 (0.41) | PDE5AFFAR2L3MBTL1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10358416-B2 | Substituted pyrrolidines as G-protein coupled receptor 43 agonists | EPICS THERAPEUTICS (BE) | 2019-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10358416-B2 | Substituted pyrrolidines as G-protein coupled receptor 43 agonists | GIPR, GPR88, GPR119 | PDE5A 820/4885FFAR2 20/4885L3MBTL1 4638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.