Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 6/20 | 0.31 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.31 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21180352 | 1.00 | KLKB1 (0.33) | KLKB1S1PR1S1PR3NR4A1HPGD | |
| SCHEMBL19780048 | 0.81 | SMN1; SMN2 (0.43) | KLKB1KDM4EKMT2ASMN1; SMN2CSNK1D | |
| SCHEMBL21179410 | 0.81 | HSP90AB1 (0.42) | KLKB1NR4A1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL19779861 | 0.78 | CYP1A2 (0.38) | KLKB1CACNA1HCACNA1GCACNA1IRORC | |
| SCHEMBL21179353 | 0.76 | KLKB1 (0.36) | KLKB1KMT2ACACNA1HCACNA1GCACNA1I | |
| SCHEMBL19780593 | 0.75 | KLKB1 (0.37) | KLKB1SMN1; SMN2 | |
| SCHEMBL19779862 | 0.74 | S1PR3 (0.38) | KLKB1S1PR3CACNA1HALDH1A1RORC | |
| SCHEMBL21177281 | 0.74 | SIRT1 (0.38) | KLKB1RORC | |
| SCHEMBL19780124 | 0.74 | GAA (0.39) | KLKB1S1PR1S1PR3HPGDKDM4E | |
| SCHEMBL21179367 | 0.73 | KLKB1 (0.36) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019142053-A2 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2019-07-25 | — | — | WO | disclosed |