Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | HIPK2 | Q9H2X6 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | TDO2 | P48775 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21180568 | 0.85 | CYP11B1 (0.40) | NPC1MAPTCYP11B1HIPK2KDM4E | |
| SCHEMBL16472926 | 0.85 | MAPT (0.37) | NPC1MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL16472939 | 0.84 | MAPT (0.36) | NPC1MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL21180663 | 0.84 | PLA2G2A (0.38) | NPC1MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL14725764 | 0.83 | MAPT (0.37) | NPC1MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL16472803 | 0.82 | MAPT (0.36) | NPC1MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL15460320 | 0.82 | MAPT (0.36) | NPC1MAPTCYP11B1KDM4EMEN1 | |
| SCHEMBL16472934 | 0.81 | CYP11B1 (0.45) | NPC1MAPTCYP11B1HIPK2KDM4E | |
| SCHEMBL15946241 | 0.81 | MAPT (0.39) | NPC1MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL21180586 | 0.80 | MAPT (0.36) | NPC1MAPTKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10361380-B2 | Heterocyclic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2019-07-23 | — | — | US | disclosed |