Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 7/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17714308 | 0.88 | PTGES (0.53) | PTGESPDE10AKDM4ELMNAPDE4D | |
| SCHEMBL17714314 | 0.83 | MAPT (0.52) | PTGESPDE10AALDH1A1KDM4ELMNA | |
| SCHEMBL31381324 | 0.80 | TDP1 (0.60) | TDP1ALDH1A1KDM4EABL1LMNA | |
| SCHEMBL31381307 | 0.79 | PDE10A (0.68) | TDP1PDE10AALDH1A1KDM4EABL1 | |
| SCHEMBL31381213 | 0.77 | PTGES (0.50) | PTGESPDE10AHTR3A | |
| SCHEMBL23714071 | 0.77 | GAA (0.62) | PTGESTDP1PDE10AKDM4EHTR3A | |
| SCHEMBL10500278 | 0.76 | ALDH1A1 (0.57) | TDP1ALDH1A1KDM4EPKMPOLB | |
| SCHEMBL4704790 | 0.75 | SMN1; SMN2 (0.51) | TDP1PDE10AALDH1A1KDM4EABL1 | |
| SCHEMBL17714481 | 0.75 | PTGES (0.73) | PTGESPDE10AALDH1A1KDM4EHTR3A | |
| SCHEMBL17714315 | 0.75 | PTGES (0.73) | PTGESPDE10AALDH1A1KDM4EHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119497709-A | Pyrimidine derivatives | ASKA 制药株式会社 | 2025-02-21 | — | — | CN | disclosed |
| EP-3221304-B1 | NOVEL CARBOXYLIC ACID COMPOUNDS USEFUL FOR INHIBITING MICROSOMAL PROSTAGLANDIN E2 SYNTHASE-1 | LILLY CO ELI (US) | 2019-07-24 | — | — | EP | disclosed |