Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2118451 | 0.88 | ALDH1A1 (0.48) | CYP2C9ALDH1A1PIK3CDLMNAMAPT | |
| SCHEMBL2119919 | 0.88 | MCL1 (0.57) | CYP2C9ALDH1A1MCL1MAPTKMT2A | |
| SCHEMBL2118662 | 0.86 | ALDH1A1 (0.61) | CYP2C9ALDH1A1GAAGFERMCL1 | |
| SCHEMBL2119981 | 0.86 | ALDH1A1 (0.60) | CYP2C9ALDH1A1GAAGFERMCL1 | |
| SCHEMBL2119785 | 0.85 | ACLY (0.59) | CA2CA9CA1CA12HTR6 | |
| SCHEMBL2118176 | 0.83 | IDH2 (0.43) | CYP2C9ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL2118824 | 0.83 | PTGES2 (0.47) | CYP2C9ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL2119905 | 0.82 | ALDH1A1 (0.50) | CYP2C9ALDH1A1MCL1LMNAMAPT | |
| SCHEMBL2117895 | 0.82 | MAPT (0.45) | CYP2C9ALDH1A1PIK3CDMAPTCA2 | |
| SCHEMBL2120031 | 0.82 | ACLY (0.44) | CYP2C9ALDH1A1GAAGFERMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095024-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | ELARA PHARMACEUTICALS GMBH (DE) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095024-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | HIF1AN, HIF1A, EGLN2 | CYP2C9 3693/4885ALDH1A1 567/4885GAA 198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.