Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.45 |
| ▸ | EDNRA | P25101 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | EEF2K | O00418 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2118236 | 0.88 | CYP2C9 (0.54) | ALDH1A1TDP1CYP3A4SMN1; SMN2MAPT | |
| SCHEMBL2118369 | 0.87 | ALDH1A1 (0.56) | ALDH1A1CYP3A4SMN1; SMN2MAPTPOLB | |
| SCHEMBL2119832 | 0.87 | ALDH1A1 (0.47) | ALDH1A1CYP3A4SMN1; SMN2MAPTCYP2C9 | |
| SCHEMBL2118244 | 0.85 | ABCB1 (0.51) | TDP1SMN1; SMN2POLBLMNAMEN1 | |
| SCHEMBL2119785 | 0.82 | ACLY (0.59) | HTR6 | |
| SCHEMBL2118176 | 0.82 | IDH2 (0.43) | ALDH1A1TDP1CYP3A4SMN1; SMN2MAPT | |
| SCHEMBL2119919 | 0.82 | MCL1 (0.57) | ALDH1A1TDP1CYP3A4SMN1; SMN2MAPT | |
| SCHEMBL2120601 | 0.80 | SMN1; SMN2 (0.53) | ALDH1A1TDP1SMN1; SMN2MAPTCYP2C9 | |
| SCHEMBL2121436 | 0.80 | POLB (0.51) | ALDH1A1TDP1CYP3A4SMN1; SMN2MAPT | |
| SCHEMBL2117625 | 0.80 | HSD17B1 (0.48) | ALDH1A1TDP1CYP3A4SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095024-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | ELARA PHARMACEUTICALS GMBH (DE) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095024-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | HIF1AN, HIF1A, EGLN2 | ALDH1A1 567/4885TDP1 1828/4885CYP3A4 3761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.