Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 6/20 | 0.35 |
| ▸ | BCHE | P06276 | 4/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18720486 | 0.89 | LMNA (0.43) | LMNATRPA1PTGS1CACNA1CACHE | |
| SCHEMBL20220018 | 0.80 | L3MBTL1 (0.40) | LMNAALDH1A1GAAALOX12SMN1; SMN2 | |
| SCHEMBL21183169 | 0.75 | — | — | |
| SCHEMBL20220255 | 0.73 | — | — | |
| SCHEMBL21183203 | 0.72 | ATM (0.39) | HTTALDH1A1ALOX12SMN1; SMN2PDK2 | |
| SCHEMBL23902035 | 0.72 | ALDH1A1 (0.33) | LMNATRPA1PTGS1CACNA1CCRHR1 | |
| SCHEMBL12593462 | 0.71 | LMNA (0.54) | LMNATRPA1PTGS1CACNA1CACHE | |
| SCHEMBL23050060 | 0.70 | LMNA (0.52) | LMNATRPA1PTGS1CACNA1CACHE | |
| SCHEMBL20220110 | 0.69 | — | — | |
| SCHEMBL23901710 | 0.69 | ALDH1A1 (0.33) | LMNATRPA1PTGS1CACNA1CHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3152216-B1 | BICYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2019-07-24 | — | — | EP | disclosed |