Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | JUN | P05412 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.32 |
| ▸ | RELA | Q04206 | 2/20 | 0.32 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21184588 | 0.80 | CCNK (0.46) | — | |
| SCHEMBL21178276 | 0.77 | HTR6 (0.40) | RORCEGFR | |
| SCHEMBL30260778 | 0.77 | HTR6 (0.40) | RORCEGFR | |
| SCHEMBL21178225 | 0.76 | DGAT1 (0.43) | RORCEGFR | |
| SCHEMBL29509186 | 0.76 | DGAT1 (0.43) | RORCEGFR | |
| SCHEMBL21178668 | 0.73 | CLK1 (0.50) | PTGES | |
| SCHEMBL30260854 | 0.73 | CLK1 (0.50) | PTGES | |
| SCHEMBL24900711 | 0.72 | EGFR (0.42) | EGFRJUNNFKB1NFKB2RELA | |
| SCHEMBL30957515 | 0.72 | EGFR (0.42) | EGFRJUNNFKB1NFKB2RELA | |
| SCHEMBL24900406 | 0.70 | EGFR (0.51) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019143730-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | SYROS PHARMACEUTICALS, INC. (US) | 2019-07-25 | — | — | WO | disclosed |