Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 13/20 | 0.46 |
| ▸ | CDK12 | Q9NYV4 | 13/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 12/20 | 0.46 |
| ▸ | CDK9 | P50750 | 12/20 | 0.46 |
| ▸ | CDK7 | P50613 | 10/20 | 0.46 |
| ▸ | CCNH | P51946 | 10/20 | 0.46 |
| ▸ | MNAT1 | P51948 | 9/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 10/20 | 0.43 |
| ▸ | CDK2 | P24941 | 10/20 | 0.43 |
| ▸ | ULK1 | O75385 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21184555 | 0.83 | CCNK (0.59) | CCNKCDK12CCNT1CDK9CDK7 | |
| SCHEMBL21184308 | 0.82 | CDK7 (0.55) | CCNKCDK12CCNT1CDK9CDK7 | |
| SCHEMBL21184300 | 0.82 | CCNK (0.59) | CCNKCDK12CCNT1CDK9CDK7 | |
| SCHEMBL21184407 | 0.80 | RORC (0.34) | — | |
| SCHEMBL21184311 | 0.79 | CDK7 (0.50) | CCNKCDK12CCNT1CDK9CDK7 | |
| SCHEMBL21184589 | 0.76 | CCNK (0.64) | CCNKCDK12CCNT1CDK9CDK7 | |
| SCHEMBL21178751 | 0.73 | CDK7 (0.46) | CCNKCDK12CCNT1CDK9CDK7 | |
| SCHEMBL30440225 | 0.71 | CCNK (0.59) | CCNKCDK12CCNT1CDK9CDK7 | |
| SCHEMBL25529565 | 0.68 | CCNE1 (0.58) | CCNKCDK12CCNT1CDK9CDK7 | |
| SCHEMBL24087425 | 0.68 | CCNK (0.56) | CCNKCDK12CCNT1CDK9CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019143730-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | SYROS PHARMACEUTICALS, INC. (US) | 2019-07-25 | — | — | WO | disclosed |