Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | STAT3 | P40763 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16594687 | 1.00 | TDP1 (0.45) | TDP1KDM4EMAPK1MAPTL3MBTL1 | |
| SCHEMBL21184515 | 1.00 | TDP1 (0.45) | TDP1KDM4EMAPK1MAPTL3MBTL1 | |
| SCHEMBL21184517 | 1.00 | TDP1 (0.45) | TDP1KDM4EMAPK1MAPTL3MBTL1 | |
| SCHEMBL22261716 | 1.00 | TDP1 (0.45) | TDP1KDM4EMAPK1MAPTL3MBTL1 | |
| SCHEMBL21184539 | 0.87 | L3MBTL1 (0.51) | TDP1KDM4EMAPK1MAPTL3MBTL1 | |
| SCHEMBL22261722 | 0.87 | L3MBTL1 (0.51) | TDP1KDM4EMAPK1MAPTL3MBTL1 | |
| SCHEMBL21184488 | 0.87 | KDM4E (0.50) | TDP1KDM4EMAPK1MAPTMAOB | |
| SCHEMBL21184455 | 0.87 | L3MBTL1 (0.51) | TDP1KDM4EMAPK1MAPTL3MBTL1 | |
| SCHEMBL21184542 | 0.87 | L3MBTL1 (0.51) | TDP1KDM4EMAPK1MAPTL3MBTL1 | |
| SCHEMBL21184489 | 0.87 | KDM4E (0.50) | TDP1KDM4EMAPK1MAPTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10364217-B2 | Chemical compounds | RESMAN AS (NO) | 2019-07-30 | — | — | US | claimed |
| EP-3052465-B1 | POLYFUNCTIONALIZED POLYETHYLENE AND POLYPROPYLENE GLYCOL USEFUL AS TRACERS | RESMAN AS (NO) | 2020-07-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10364217-B2 | Chemical compounds | PTGES, PTGIS, PTGFR | TDP1 2958/4885KDM4E 4601/4885MAPK1 2127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.