Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21185379 | 0.91 | CRHBP (0.42) | ALDH1A1MEN1KMT2ALMNAHTT | |
| SCHEMBL21185257 | 0.88 | PIK3CD (0.48) | ALDH1A1MEN1KMT2ALMNAHTT | |
| SCHEMBL21178215 | 0.84 | PIK3CD (0.37) | ALDH1A1LMNAHTTNPSR1MAPT | |
| SCHEMBL21178492 | 0.83 | NPSR1 (0.38) | ALDH1A1LMNAMAPK1NPSR1MAPT | |
| SCHEMBL16597161 | 0.82 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2ALMNAHTT | |
| SCHEMBL16597162 | 0.81 | HSP90AB1 (0.49) | ALDH1A1MEN1KMT2ALMNAHTT | |
| SCHEMBL16597166 | 0.81 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ALMNAHTT | |
| SCHEMBL21174746 | 0.79 | PIK3CD (0.46) | PIK3CDPIK3R1PIK3CGPIK3CA | |
| SCHEMBL21174744 | 0.79 | PIK3CD (0.46) | PIK3CDPIK3R1PIK3CGPIK3CA | |
| SCHEMBL21185262 | 0.79 | PIK3CD (0.49) | PDE10APIK3CDPIK3R1PIK3CGCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019143874-A1 | SUBSTITUTED AMINOPYRIMIDINE COMPOUNDS AND METHODS OF USE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2019-07-25 | — | — | WO | disclosed |