Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 4/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 3/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21185496 | 0.87 | PDGFRA (0.58) | SRCTGFBR1PDGFRAKDRPDGFRB | |
| SCHEMBL26254967 | 0.74 | MET (0.56) | PDGFRAKDRPDGFRBMETFGFR2 | |
| SCHEMBL371742 | 0.74 | MET (0.58) | PDGFRAKDRPDGFRBMETFGFR2 | |
| SCHEMBL30106509 | 0.74 | MET (0.58) | PDGFRAKDRPDGFRBMETFGFR2 | |
| SCHEMBL12023929 | 0.73 | AXL (0.62) | SRCPDGFRAKDRMET | |
| SCHEMBL12829632 | 0.73 | PDGFRB (0.53) | SRCTGFBR1PDGFRAPDGFRBMET | |
| SCHEMBL15338440 | 0.72 | PDGFRA (0.48) | PDGFRAKDRMET | |
| SCHEMBL23158610 | 0.72 | FGFR2 (0.58) | PDGFRAKDRPDGFRBMETIGF1R | |
| SCHEMBL30106564 | 0.71 | PDGFRA (0.60) | PDGFRAKDRPDGFRBMET | |
| SCHEMBL21769162 | 0.71 | MET (0.56) | PDGFRAKDRPDGFRBMETIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3329918-B1 | C-MET MODULATORS AND METHODS OF USE | EXELIXIS INC (US) | 2022-05-25 | — | — | EP | disclosed |