SCHEMBL21186191

SCHEMBL21186191

Cc1cc(N2CCN(c3ccnc(C)c3)CC2)ccn1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 5/20 0.50
UHRF1 Q96T88 1/20 0.48
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
GLA P06280 1/20 0.46
GAA P10253 1/20 0.46
AOC3 Q16853 1/20 0.44
CCR1 P32246 1/20 0.43
CCR5 P51681 1/20 0.43
CCR8 P51685 1/20 0.43
NPC1 O15118 2/20 0.42
MAPT P10636 1/20 0.42
LDHA P00338 1/20 0.41
KDM4E B2RXH2 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CHRM1 P11229 1/20 0.40
PRDM9 Q9NQV7 1/20 0.40
PRDM7 Q9NQW5 1/20 0.40
RXRA P19793 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13027974 0.92 HRH4 (0.61) HRH4MEN1KMT2AGLAGAA
SCHEMBL425041 0.92 HRH4 (0.56) HRH4UHRF1MEN1KMT2AGAA
SCHEMBL7010820 0.91 HRH4 (0.44) HRH4UHRF1MEN1KMT2AGLA
Water SCHEMBL28114608 0.90 HRH4 (0.54) HRH4UHRF1MEN1KMT2AGAA
SCHEMBL9455784 0.90 HRH4 (0.58) HRH4UHRF1MEN1KMT2AGLA
SCHEMBL10682305 0.88 MAPT (0.53) HRH4MEN1KMT2AGLAGAA
SCHEMBL7016194 0.88 HRH4 (0.42) HRH4UHRF1MEN1KMT2AGLA
SCHEMBL10771091 0.88 HRH4 (0.42) HRH4UHRF1MEN1KMT2AGLA
SCHEMBL11981573 0.87 TP53 (0.49) MEN1KMT2ANPC1MAPTKDM4E
SCHEMBL2798864 0.87 ADRB2 (0.56) HRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240019738-A1 DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF JAPAN DISPLAY INC. (JP) 2024-01-18 US disclosed
US-20240019738-A1 DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF JAPAN DISPLAY INC. (JP) 2024-01-18 US disclosed
WO-2019189632-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2019-10-03 WO disclosed
WO-2019142927-A1 LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME 日産化学株式会社 2019-07-25 WO disclosed