Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.58 |
| ▸ | CHKA | P35790 | 1/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 2/20 | 0.46 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.46 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | S100B | P04271 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL425041 | 0.98 | HRH4 (0.56) | HRH4CHKACD274TERTELOVL1 | |
| Water SCHEMBL28114608 | 0.96 | HRH4 (0.54) | HRH4CHKACD274TERTELOVL1 | |
| SCHEMBL21186191 | 0.90 | HRH4 (0.50) | HRH4CHKAUHRF1GAAMEN1 | |
| SCHEMBL13027958 | 0.84 | HRH4 (0.63) | HRH4CHKAGAAMEN1KMT2A | |
| SCHEMBL13027974 | 0.83 | HRH4 (0.61) | HRH4ALDH1A1GAAMEN1MAPT | |
| SCHEMBL2798864 | 0.81 | ADRB2 (0.56) | HRH4HTT | |
| SCHEMBL7010820 | 0.81 | HRH4 (0.44) | HRH4UHRF1GAAMEN1MAPT | |
| SCHEMBL11981573 | 0.81 | TP53 (0.49) | ALDH1A1MEN1MAPTALOX15MAPK1 | |
| SCHEMBL20899424 | 0.81 | UHRF1 (0.41) | HRH4CHKACD274UHRF1 | |
| SCHEMBL24767206 | 0.80 | LDHA (0.45) | HRH4UHRF1ALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021004467-A1 | COMPOUND AS PORCUPINE INHIBITOR AND USE THEREOF | 南京明德新药研发有限公司 | 2021-01-14 | — | — | WO | disclosed |
| US-8802679-B2 | Glycine compound | ASTELLAS PHARMA INC. (JP) | 2014-08-12 | — | — | US | disclosed |
| US-20120184520-A1 | GLYCINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2012-07-19 | — | — | US | disclosed |
| US-5250527-A | Enzyme inhibitors; administering to reduce gastric acid secretion | SMITHKLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-10-05 | — | — | US | disclosed |
| WO-1992021317-A1 | PYRIDINE 1-OXIDE BASED COMPOSITION FOR COMBATTING HAIR LOSS AND FOR INDUCING AND STIMULATING HAIR GROWTH | L'OREAL (FR) | 1992-12-10 | — | — | WO | disclosed |
| EP-0184322-B1 | BENZIMIDAZOLES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1989-12-20 | — | — | EP | disclosed |
| EP-0184322-A1 | Benzimidazoles | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1986-06-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120184520-A1 | GLYCINE COMPOUND | SLC5A1, AQP1, VAPB | HRH4 2095/4885CHKA 4112/4885CD274 2651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.