SCHEMBL21186397

SCHEMBL21186397

Fc1ccc(F)c2nc3c(nc12)c1nc2c(F)ccc(F)c2nc1c1nc2c(F)ccc(F)c2nc31

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.34
ALDH1A1 P00352 2/20 0.33
GAA P10253 2/20 0.33
KDM4E B2RXH2 2/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
PRNP P04156 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
MAPT P10636 1/20 0.31
MPI P34949 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25175974 0.78 TDP1 (0.39) SMN1; SMN2ALDH1A1GAAKDM4EMEN1
SCHEMBL7453021 0.68 CCR1 (0.37) SMN1; SMN2MEN1NPC1RAB9AKMT2A
SCHEMBL1170827 0.64 PTGES (0.37) ALDH1A1GAAKDM4EMEN1NPC1
SCHEMBL12076420 0.63
SCHEMBL2252282 0.62
SCHEMBL15624392 0.60
SCHEMBL23036767 0.60
SCHEMBL45430 0.59 CES2 (0.53) ALDH1A1LMNA
SCHEMBL18606165 0.59 CA3 (0.35)
SCHEMBL21297318 0.57 MAPT (0.40) SMN1; SMN2ALDH1A1GAAKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190229151-A1 PHOTOELECTRIC CONVERSION ELEMENT AND SOLID-STATE IMAGING APPARATUS SONY SEMICONDUCTOR SOLUTIONS CORPORATION (JP) 2019-07-25 US disclosed