Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GHSR | Q92847 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2117938 | 0.88 | SMN1; SMN2 (0.50) | MAPTTP53SMN1; SMN2HSD11B1POLB | |
| SCHEMBL2118455 | 0.88 | HSD11B1 (0.60) | MAPTTP53SMN1; SMN2HSD11B1POLB | |
| SCHEMBL2120050 | 0.83 | RET (0.51) | MAPTTP53SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2120080 | 0.80 | MCL1 (0.60) | MAPTTP53SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL2118662 | 0.78 | ALDH1A1 (0.61) | MAPTPOLBALDH1A1GAAGFER | |
| SCHEMBL2122197 | 0.78 | ALDH1A1 (0.51) | MAPTPOLBALDH1A1GAAGFER | |
| SCHEMBL2119832 | 0.78 | ALDH1A1 (0.47) | MAPTTP53SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL2119880 | 0.77 | BRD4 (0.47) | MAPTTP53SMN1; SMN2POLBKMT2A | |
| SCHEMBL2120534 | 0.76 | ABCB1 (0.51) | SMN1; SMN2POLBMAPK14 | |
| SCHEMBL2119478 | 0.76 | HSD17B2 (0.53) | MAPTTP53SMN1; SMN2POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095024-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | ELARA PHARMACEUTICALS GMBH (DE) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095024-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | HIF1AN, HIF1A, EGLN2 | MAPT 4523/4885TP53 193/4885SMN1; SMN2 3684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.